Research Article
Alpha-Thalassemia in North Morocco: Prevalence and Molecular Spectrum
Table 3
Hematologic features and hemoglobin Bart’s levels by genotype.
| Genotype | Province | Hb (g/dl) | MCV (fl) | MCH (pg) | Hb Bart’s % | Tangier Assilah Fahs-Anjra | Tetouan M’diq Fnideq | Larache |
| -α3.7/ αα | 2 | 1 | 3 | 11.5 | 126.2 | 35.4 | 0.8 | 13.1 | 92.6 | 29.2 | 0 | 13.5 | 94.7 | 29.9 | 1.8 | 12.5 | 92.5 | 28.7 | 0.45 | 15.5 | 93.5 | 29.6 | 0.9 | 12.5 | 94 | 33.8 | 0 |
| -α3 .7/-α3.7 | 0 | 0 | 2 | 11.1 | 95.9 | 29.9 | 1.8 | 13.3 | 98.5 | 31.5 | 2.3 |
| - /αα | 0 | 0 | 1 | 11.8 | 96.3 | 30.3 | 1.3 |
| αα/αα | 1 | 0 | 1 | 11.2 | 93.3 | 28.5 | 0 | 11.4 | 93.7 | 28.9 | 0 |
| -α4.2/ αα | 0 | 0 | 2 | 11.9 | 95.6 | 28.3 | 0.4 | 13.2 | 91 | 31.9 | 1 |
| -α4.2/ -α4.2 | 0 | 1 | 0 | 12.7 | 92.7 | 29.9 | 3 |
| αα/ αα with HS-40 del | 0 | 0 | 1 | 11.2 | 92.4 | 29.8 | 1.1 |
| - -/αα | 0 | 0 | 1 | 12.1 | 88.5 | 29.5 | 5.2 |
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Hb: hemoglobin, MCV: mean corpuscular volume, MCH: mean corpuscular hemoglobin.
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