Research Article
Genotypes and Hot Spot Mutations of Hepatitis B Virus in Northwest Chinese Population and Its Correlation with Diseases Progression
Table 5
Patients with nt 1762/1764/1896/1899 mutations vulnerable to HBeAg negativity.
| | HBeAg | OR (95% CI) | | Negative (%) | Positive (%) |
| Control | 30 (32.26%) | 63 (67.74%) | | | BCP mutant core (A1762/G1764 double only) | 17 (53.13%) | 15 (46.88%) | 2.38 (1.05, 5.40) | 0.038 | Coincidence (A1762 and/or G1764/G1896 and/or G1899, triple/quadruples) | 169 (80.09%) | 42 (19.91%) | 8.45 (4.87, 14.66) | <0.01 |
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