Research Article

Genotypes and Hot Spot Mutations of Hepatitis B Virus in Northwest Chinese Population and Its Correlation with Diseases Progression

Table 5

Patients with nt 1762/1764/1896/1899 mutations vulnerable to HBeAg negativity.

HBeAgOR (95% CI)
Negative (%)Positive (%)

Control30 (32.26%)63 (67.74%)
BCP mutant core (A1762/G1764 double only)17 (53.13%)15 (46.88%)2.38 (1.05, 5.40)0.038
Coincidence (A1762 and/or G1764/G1896 and/or G1899, triple/quadruples)169 (80.09%)42 (19.91%)8.45 (4.87, 14.66)<0.01