Effect of Hydrotalcite on Indometacin-Induced Gastric Injury in Rats

Figure 4

(a) Immunohistochemical staining of EGF in gastric mucosa in therapeutic experiment (200X). Positive cells were stained brown-yellow. (b) Immunohistochemical staining of COX-1 in gastric mucosa in therapeutic experiment (200X). Positive cells were stained brown-yellow. Labels are the same as Figure 4(a). The expression of COX-1 in ranitidine group was the highest. (c) Immunohistochemical staining of COX-2 in gastric mucosa in therapeutic experiment (200X). Positive cells were stained brown-yellow. Labels are the same as Figure 4(a). The expression of COX-2 in omeprazole group was the highest. A: vehicle group, B: model group, and C: omeprazole group, the expression of EGF was the highest. D: hydrotalcite group, E: ranitidine group.

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