Review Article

Effect of Weightlessness on the 3D Structure Formation and Physiologic Function of Human Cancer Cells

Table 4

The basic experimental conditions of human cancer cells involved genes changes under real or simulated microgravity.

Samples(cell line) Exposure DevicesExposure timeRef.

FTC-133 thyroid cancer cellss-μg/RPM24 h[35]
FTC-133 thyroid cancer cellsr-μg / Shenzhou 8 space mission and s-μg / RPM10 d[48]
FTC-133 thyroid cancer cellsr-μg / Shenzhou 10 space mission and s-μg / RPM10 d[31]
MCF-7 breast cancer cellss-μg/RPM5 d[50]
L-540 and HDLM-2 Hodgkin’s
lymphoma cancer cells
s-μg / 3D Clinostat3 d[51]

Table 4. d, day; RPM, rounds per minute. r-μg, real microgravity; s-μg, simulated microgravity; RPM: Random Positioning Machine.