BioMed Research International / 2020 / Article / Tab 7

Research Article

Association of EPAS1 and PPARA Gene Polymorphisms with High-Altitude Headache in Chinese Han Population

Table 7

Distribution of rs4953354 and rs6520015 in HAH and non-HAH groups.

SubgroupsHAH+ [n (%)]HAH− [n (%)]OR (95% CI) valueOR (95% CI)a valuea

1237 (56.29)66 (41.51)11
265 (15.44)30 (18.87)0.60 (0.36–1.01)0.0530.60 (0.35–1.02)0.059
394 (22.33)43 (27.04)0.61 (0.39–0.96)0.0320.63 (0.40–0.99)0.049
425 (5.94)20 (12.58)0.35 (0.18–0.67)0.0010.36 (0.18–0.70)0.003

Subgroup 1: subjects carrying neither rs4953354 “AG/GG” nor rs6520015 “CT/CC”; subgroup 2: subjects carrying rs4953354 “AG/GG” but not rs6520015 “CT/CC”; subgroup 3: subjects carrying rs6520015 “CT/CC” but not rs4953354 “AG/GG”; subgroup 4: subjects carrying both rs4953354 “AG/GG” and rs6520015 “CT/CC”. aAdjusted for age, height, weight, BMI, smoking and drinking status, HR, SpO2, SBP, and DBP. indicated statistical significance. HAH+, subjects with HAH; HAH−, subjects without HAH. See Table 3 for group abbreviations.