miR-876 Inhibits EMT and Liver Fibrosis via POSTN to Suppress Metastasis in Hepatocellular Carcinoma

Figure 5

POSTN was associated with EMT and liver cirrhosis in clinical HCC tissues. (a–c) Animal experiments, the luciferase intensities were measured each week (c) after intracapsular injection with NC (a) or ov miR-876 (b) HCC-LM3 cells in the liver, liver cancer in situ (the red arrows point to), were showed by autopsy (a, b). (d) The expression of POSTN was detected in HCC samples with or without tumor thrombus. (e) The expression of POSTN was detected in HCC samples with or without liver cirrhosis. (f–i) Immunohistochemical staining of POSTN and EMT markers in HCC tissues; representative images of POSTN (f), E-cadherin (g), N-cadherin (h), or vimentin (i) immunostaining of low or high, respectively. (j) Representative image of POSTN immunostaining in HCC with liver cirrhosis tissue.

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