Influence of Geographical and Seasonal Variations on Carbazole Alkaloids Distribution in Murraya koenigii: Deciding Factor of Its In Vitro and In Vivo Efficacies against Cancer Cells

Figure 4

Geographical variations of mahanine, mahanimbine, and koenimbine and its relation with antiproliferative activity. (a) Morphological differences in leaflets collected from nine different locations. (b) Locations for leaflets collection were marked on the map; highlights with black, green, and red dots represent the low, medium, and high quantities of mahanine. (c) The percent of mahanine in MEFs prepared from different places. (d) IC50 values of MEFs were checked for their activity against PA1 for 48 h by the MTT assay. These results were compared with mahanine quantity as depicted in Figure 4(d). These data were derived from three individual experiments, and mean ± SD was indicated.

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