Protective Effects of MitoTEMPO on Nonalcoholic Fatty Liver Disease via Regulating Myeloid-Derived Suppressor Cells and Inflammation in Mice
The frequency of CD11b+Gr-1+ MDSCs in mice. (a) Flow cytometry analysis of CD11b+Gr-1+ MDSCs in peripheral blood of the lean (left), HFD (middle), and HFD+Mito (right) groups. (b) Representative quantification of CD11b+Gr-1+ MDSCs in the three groups. Data are represented as the . HFD vs. lean: , HFD+Mito vs. HFD: n.s: no significant difference, unpaired -test. (c) Gr-1 immunohistochemistry images in the lean (left), HFD (middle), and HFD+Mito (right) groups. Scale bar, 100 μm.
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