Research Article
Circular RNA circPVT1 Contributes to Doxorubicin (DXR) Resistance of Osteosarcoma Cells by Regulating TRIAP1 via miR-137
Figure 8
circPVT1 knockdown inhibited tumor growth in osteosarcoma cells in vivo. (a, b) Tumor volume and tumor weight were detected in xenografts. (c) The levels of circPVT1, miR-137, and TRIAP1 in xenografts were assessed by RT-qPCR assay. (d) TRIAP1 protein level was measured in xenografts by western blot assay. (e) The protein levels of Bcl-2, c-caspase-3, ABCB1, and MRP-1 were examined in xenografts. .
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