BioMed Research International

Oncogenic Processes


Publishing date
12 Jul 2013
Status
Published
Submission deadline
02 Apr 2013

1Laboratory of Genetics, Instituto Butantan, São Paulo, SP, Brazil

2Department of Pathology and Animal Health, The University of Naples Federico II, Naples, Italy

3Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, Scotland


Oncogenic Processes

Description

The relevance of cancer to human health is extremely high, and the efforts to understand and control the processes related to the oncogenic modifications in cells have increased dramatically in the past few decades. The remarkable contribution of Zur Hausen in describing the virus oncogenic action led to new approaches in cancer studies. Several neoplastic diseases have been reported discussing virus causal action. Furthermore, environmental agents were also verified as cofactors acting in the cell transformation infected by viruses. Considering these aspects, the papillomaviruses play a major role in human and animal carcinogenesis. These viruses have been described in many groups of vertebrates, with great importance in mammals. In bovines, they act in the development of benign cutaneous lesions and malign lesions in bladder and digestive system, associated to cofactors as the bracken fern, Pteridium aquilinum. In equines, they induce sarcoid. Obviously, these diseases lead to serious economic hazards. But, none of these events are as dramatic as the relationship between human papillomavirus (HPV) and human cervical cancer. Second major cause of death in women, the cervical cancer is related to a group of HPVs, the high risk group. Many studies are being developed reaching either for the cure as such as for prophylactic aim. The cooperation of viruses and environmental cofactors is an excellent model to the understanding of oncogenic processes.

We invite investigators working in the field of oncogenic processes to contribute original research articles as well as review articles. Potential topics include, but are not limited to:

  • The biological roles of the genes involved in cell cycle regulation
  • Cancer development
  • Technologies available for diagnosis and novel prophylactic and therapeutic strategies

The large number of related issues to oncogenic process demands that many other aspects shall be considered in the invited contributions, such as cancer stem cells, cell mutations, apoptosis, oxidative stress, epigenetic modifications, inflammation, and bioinformatics. Review articles should provide a comprehensive overview of the current knowledge, as well as outline the challenges and the open issues in the field.

This special issue will be dedicated to the 80th anniversary of Professor Dr. Willy Beçak, former Director of Instituto Butantan, São Paulo, Brazil, and remarkable Senior Researcher in Genetics.

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/biomed/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/biomed/oncology/op/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 879013
  • - Editorial

Oncogenic Processes

Rita de Cassia Stocco | Franco Peppino Roperto | ... | Marcelo Palma Sircili
  • Special Issue
  • - Volume 2014
  • - Article ID 675985
  • - Review Article

State of the Art in the Studies on Crotamine, a Cell Penetrating Peptide from South American Rattlesnake

Irina Kerkis | Mirian A. F. Hayashi | ... | Tetsuo Yamane
  • Special Issue
  • - Volume 2013
  • - Article ID 578276
  • - Research Article

Persistence or Clearance of Human Papillomavirus Infections in Women in Ouro Preto, Brazil

P. M. Miranda | N. N. T. Silva | ... | A. A. Lima
  • Special Issue
  • - Volume 2013
  • - Article ID 618475
  • - Research Article

Higher Incidence of Lung Adenocarcinomas Induced by DMBA in Connexin 43 Heterozygous Knockout Mice

Krishna Duro de Oliveira | Marcello Vannucci Tedardi | ... | Maria Lúcia Zaidan Dagli
  • Special Issue
  • - Volume 2013
  • - Article ID 976816
  • - Research Article

The Human Cell Surfaceome of Breast Tumors

Júlia Pinheiro Chagas da Cunha | Pedro Alexandre Favoretto Galante | ... | Sandro José de Souza
  • Special Issue
  • - Volume 2013
  • - Article ID 630683
  • - Research Article

Bovine Papillomavirus Clastogenic Effect Analyzed in Comet Assay

R. P. Araldi | T. C. Melo | ... | R. C. Stocco
  • Special Issue
  • - Volume 2013
  • - Article ID 283985
  • - Research Article

Analysis of Activated Platelet-Derived Growth Factor β Receptor and Ras-MAP Kinase Pathway in Equine Sarcoid Fibroblasts

Gennaro Altamura | Annunziata Corteggio | ... | Giuseppe Borzacchiello
  • Special Issue
  • - Volume 2013
  • - Article ID 421398
  • - Research Article

Expression and In Silico Analysis of the Recombinant Bovine Papillomavirus E6 Protein as a Model for Viral Oncoproteins Studies

J. Mazzuchelli-de-Souza | R. F. Carvalho | ... | R. C. Stocco
  • Special Issue
  • - Volume 2013
  • - Article ID 297692
  • - Research Article

Interference with RUNX1/ETO Leukemogenic Function by Cell-Penetrating Peptides Targeting the NHR2 Oligomerization Domain

Yvonne Bartel | Manuel Grez | Christian Wichmann
  • Special Issue
  • - Volume 2013
  • - Article ID 270898
  • - Research Article

Bovine Papillomavirus in Brazil: Detection of Coinfection of Unusual Types by a PCR-RFLP Method

R. F. Carvalho | S. T. Sakata | ... | R. C. Stocco
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
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