BioMed Research International

Biomarkers of Metabolic Disorders: Diagnostic and Prognostic Values and Insights into the Pathogenesis

Publishing date
01 Aug 2014
Submission deadline
14 Mar 2014

Lead Editor
Guest Editors

1Translational Medical Center, Shanghai Diabetes Institute, Shanghai Jiao Tong University Affiliated to Sixth People’s Hospital, Shanghai 200233, China

2Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

3University of Hawaii Cancer Center, Honolulu, HI, USA

Biomarkers of Metabolic Disorders: Diagnostic and Prognostic Values and Insights into the Pathogenesis


In recent decades, overwhelming evidence has indicated that metabolic disorders, including obesity, diabetes, dyslipidemia, and nonalcohol fatty liver disease, are the leading cause of disability and death. However, the pathogenesis of metabolic disorder and its chronic complications involve multiple biological pathways and are largely unknown. Biological markers, or biomarkers, are alterations and biological characteristics that can be evaluated as indicators of pathogenic processes or pharmacological responses to therapeutic interventions. In consequence, it is imperative for researchers to search for the biomarkers of the metabolic disorders using systemic biology approaches and evaluate their effects in different ethnic populations, which may provide potential diagnostic markers as well as drug targets for the disease and shed more light on the mechanisms.

This special issue mainly focuses on the current advancement in the field of biomarkers of metabolic disorders. We cordially invite scientists and investigators to contribute both your original research manuscripts and review articles that will stimulate the further research activities in this rising field and enhance our existing knowledge of biomarkers in metabolic disorders. Potential topics include, but are not limited to:

  • Studies searching for genetic and genomic markers for metabolic disorders
  • Proteomic and metabolomic studies searching for biomarkers for metabolic disorders
  • Studies evaluating the diagnostic and prognostic effects of biomarkers and metabolic disorders in different ethnic populations
  • Mechanism studies derived from known biomarkers to explicit the pathogenesis of diseases
  • Latest technologies for promoting the new discoveries of biomarkers
  • Reviews addressing issues related to the accomplishment of biomarkers and their applications

Before submission, authors should carefully read over the journal’s Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:


  • Special Issue
  • - Volume 2014
  • - Article ID 586272
  • - Editorial

Biomarkers of Metabolic Disorders: Diagnostic and Prognostic Values, and Insights into the Pathogenesis

Cheng Hu | Jiarui Wu | Wei Jia
  • Special Issue
  • - Volume 2014
  • - Article ID 946492
  • - Research Article

Effects of the Angiotensin Receptor Blocker Olmesartan on Adipocyte Hypertrophy and Function in Mice with Metabolic Disorders

Akinobu Maeda | Kouichi Tamura | ... | Satoshi Umemura
  • Special Issue
  • - Volume 2014
  • - Article ID 869186
  • - Research Article

Breath Ketone Testing: A New Biomarker for Diagnosis and Therapeutic Monitoring of Diabetic Ketosis

Yue Qiao | Zhaohua Gao | ... | Yu Liu
  • Special Issue
  • - Volume 2014
  • - Article ID 406909
  • - Research Article

CCAAT/Enhancer-Binding Protein α Is a Crucial Regulator of Human Fat Mass and Obesity Associated Gene Transcription and Expression

Wei Ren | Jianjin Guo | ... | Weiping Jia
  • Special Issue
  • - Volume 2014
  • - Article ID 926713
  • - Review Article

Genetics of Type 2 Diabetes: Insights into the Pathogenesis and Its Clinical Application

Xue Sun | Weihui Yu | Cheng Hu
  • Special Issue
  • - Volume 2014
  • - Article ID 704167
  • - Research Article

Lack of Association between TLR4 Genetic Polymorphisms and Diabetic Nephropathy in a Chinese Population

Danfeng Peng | Jie Wang | ... | Weiping Jia
  • Special Issue
  • - Volume 2014
  • - Article ID 912052
  • - Research Article

A Novel Mutation in Leptin Gene Is Associated with Severe Obesity in Chinese Individuals

Yue Zhao | Nanchao Hong | ... | Weiping Jia
  • Special Issue
  • - Volume 2013
  • - Article ID 238150
  • - Research Article

Association of Genetic Variants of BMP4 with Type 2 Diabetes Mellitus and Clinical Traits in a Chinese Han Population

Shanshan Tang | Rong Zhang | ... | Weiping Jia
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