BioMed Research International

Antimicrobial Peptides: Current and Potential Applications in Biomedical Therapies


Status
Published

1Centro Multidisciplinario de Estudios en Biotecnología, Universidad Michoacana de San Nicolás de Hidalgo,. Km. 9.5 Carretera Morelia-Zinapécuaro, C.P. 58893, Morelia, Michoacán, Mexico

2División de Ciencias de la Vida, Departamento de Alimentos, Universidad de Guanajuato, Campus Irapuato-Salamanca, 36500, Irapuato, Guanajuato, Mexico

3Department of Entomology, University of California Riverside, Riverside, CA 92521, USA


Antimicrobial Peptides: Current and Potential Applications in Biomedical Therapies

Description

The evolution of pathogenic bacteria has allowed many microbes to develop resistance mechanisms against conventional antibiotics, leading to the search for new therapeutic alternatives. As such, the clinical uses of antimicrobial peptides (AMPs) are among the most promising alternative options to circumvent the proliferation of antibiotic-resistant pathogens. AMPs are produced by a wide variety of organisms and have a broad and largely non-specific activity, a characteristic that strongly qualifies them as potent candidates for pharmacological applications. Indeed, the continuous discovery of new AMP groups in diverse microorganisms has expanded their potential as a new generation of antimicrobial agents for treating bacterial diseases in humans and also in animals. Intriguingly, the broad spectrum of biological activities reported for many of these molecules suggests that AMPs could also be incorporated in integrative regimen strategies against viral, fungal, parasitic diseases, and cancer, as well as in modulation of the immune system. These possibilities reinforce the importance of studying the biological and applied properties of AMPs.

This special issue focuses mainly on original research and review articles that highlight the importance of AMPs in the natural biology of microorganisms, including bacterial cell communication processes, their potential applied use in human and veterinary medicine, and immune response modulation in animals and plant defenses. Potential topics include, but are not limited to:

Natural or Synthetic Antimicrobial Peptides as

  • Anti-infectious agents including AMPs with antibacterial, -fungal, -viral, or -protozoan activities
  • Novel cancer therapeutics including cytotoxic peptides or apoptosis inductors
  • Immunomodulatory agents including modulators of innate and adaptive responses

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/microbiology/peptid/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 367243
  • - Editorial

Antimicrobial Peptides: Current and Potential Applications in Biomedical Therapies

Joel E. López-Meza | Alejandra Ochoa-Zarzosa | ... | Dennis K. Bideshi
  • Special Issue
  • - Volume 2015
  • - Article ID 197608
  • - Research Article

Cytotoxicity of Cyclodipeptides from Pseudomonas aeruginosa PAO1 Leads to Apoptosis in Human Cancer Cell Lines

Dolores Vázquez-Rivera | Omar González | ... | Jesús Campos-García
  • Special Issue
  • - Volume 2015
  • - Article ID 767183
  • - Research Article

Cloning and Expression of Synthetic Genes Encoding the Broad Antimicrobial Spectrum Bacteriocins SRCAM 602, OR-7, E-760, and L-1077, by Recombinant Pichia pastoris

Sara Arbulu | Juan J. Jiménez | ... | Pablo E. Hernández
  • Special Issue
  • - Volume 2015
  • - Article ID 453826
  • - Research Article

Antibacterial Activity of Synthetic Peptides Derived from Lactoferricin against Escherichia coli ATCC 25922 and Enterococcus faecalis ATCC 29212

María A. León-Calvijo | Aura L. Leal-Castro | ... | Zuly J. Rivera-Monroy
  • Special Issue
  • - Volume 2015
  • - Article ID 189016
  • - Review Article

Current and Potential Applications of Host-Defense Peptides and Proteins in Urology

Joey Chor Yee Lo | Dirk Lange
  • Special Issue
  • - Volume 2015
  • - Article ID 430436
  • - Research Article

Effect of Recombinant Prophenin 2 on the Integrity and Viability of Trichomonas vaginalis

J. L. Hernandez-Flores | M. C. Rodriguez | ... | E. E. Avila
  • Special Issue
  • - Volume 2015
  • - Article ID 615153
  • - Research Article

Molecular Detection and Sensitivity to Antibiotics and Bacteriocins of Pathogens Isolated from Bovine Mastitis in Family Dairy Herds of Central Mexico

Ma. Fabiola León-Galván | José E. Barboza-Corona | ... | Abner J. Gutierrez-Chavez
  • Special Issue
  • - Volume 2015
  • - Article ID 714580
  • - Research Article

Ascorbic Acid, Ultraviolet C Rays, and Glucose but not Hyperthermia Are Elicitors of Human β-Defensin 1 mRNA in Normal Keratinocytes

Luis Antonio Cruz Díaz | María Guadalupe Flores Miramontes | ... | Ernesto Prado Montes de Oca
  • Special Issue
  • - Volume 2015
  • - Article ID 102129
  • - Review Article

Biologically Active and Antimicrobial Peptides from Plants

Carlos E. Salas | Jesus A. Badillo-Corona | ... | Carmen Oliver-Salvador
  • Special Issue
  • - Volume 2015
  • - Article ID 735087
  • - Review Article

Plant Antimicrobial Peptides as Potential Anticancer Agents

Jaquelina Julia Guzmán-Rodríguez | Alejandra Ochoa-Zarzosa | ... | Joel E. López-Meza
BioMed Research International
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Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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