BioMed Research International

The Use of Natural Polysaccharides as Biomaterials


Status
Published

Lead Editor

1Institute of Polymer Chemistry and Technology, Pozzuoli, Italy

2Universidade Católica Portuguesa, Porto, Portugal

3French Research Institute for Exploitation of the Sea (Ifremer), Nantes, France

4Marinova Pty Ltd., Cambridge, Australia


The Use of Natural Polysaccharides as Biomaterials

Description

The interest of scientists towards polysaccharides of natural origin has grown in the last ten years. We are witnessing a renaissance of natural polysaccharides, as they match the requirement of environment friendly extraction and processing methodologies, abundance, versatility, potential biocompatibility and biodegradability, renewable sources, low processing costs, tailoring of structure by genetic manipulation, and so on. Moreover, the good chemical reactivity and possibility to use a rather simple chemistry allows modifying their final properties.

Natural polysaccharides are mainly used in pharmaceuticals, as drug carriers or antimicrobial, anti-inflammatory, or coagulation modifying agents, in tissue engineering and wound dressings, and, due to their mild gelling conditions, for immobilization of cells and enzymes. In opportune conditions, the gelation process can be slowed down, and this is of interest for in situ injectable gels. Hyaluronic acid, the main component of connective tissue, is at present the diamond tip among heteropolysaccharides, and it is largely used topically in cosmetics and in medicine as biomaterial for cartilage repair and tissue bulking agent.

We invite investigators to contribute original research articles as well as review articles that will stimulate the interest of the reader towards the possibility to fortify and extend the field of biomedical applications of polysaccharides. We are particularly interested in articles describing the characterization and potential biomedical applications of new exopolysaccharides, as well as novel chemical and enzymatic modification strategies of common polysaccharides, their blending with other biopolymers, and addition of biodegradable additives, with description of their potentiality in biomedical field.

Potential topics include, but are not limited to:

  • Preparation of copolymers in different architectures (such as amphiphilic polymers)
  • Biosynthesis and modification (chemical or enzymatic) of polysaccharides
  • Carriers for sustained drug release and gene therapy (such as micelles and micro- and nanoparticles)
  • Tissue engineering scaffolds, fabrication methods (i.e. electrospinning), and materials in different forms (hydrogels, foams, nanofibers, patches, etc.)
  • New or improved application of existing polysaccharides
  • Bioactive properties and host response
  • Hybrid biomaterials

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 242378
  • - Editorial

The Use of Natural Polysaccharides as Biomaterials

Paola Laurienzo | João C. Fernandes | ... | J. Helen Fitton
  • Special Issue
  • - Volume 2015
  • - Article ID 403413
  • - Research Article

Prevention of Polyglycolic Acid-Induced Peritoneal Adhesions Using Alginate in a Rat Model

Mari Matoba | Ayumi Hashimoto | ... | Akeo Hagiwara
  • Special Issue
  • - Volume 2015
  • - Article ID 965804
  • - Research Article

Insights in Behavior of Variably Formulated Alginate-Based Microcapsules for Cell Transplantation

Pia Montanucci | Silvia Terenzi | ... | Riccardo Calafiore
  • Special Issue
  • - Volume 2015
  • - Article ID 392940
  • - Research Article

Preparation of Porous Chitosan-Siloxane Hybrids Coated with Hydroxyapatite Particles

Yuki Shirosaki | Kohei Okamoto | ... | Takuji Asano
  • Special Issue
  • - Volume 2015
  • - Article ID 508656
  • - Research Article

A Direct Sulfation Process of a Marine Polysaccharide in Ionic Liquid

Nathalie Chopin | Corinne Sinquin | ... | Sylvia Colliec-Jouault
  • Special Issue
  • - Volume 2015
  • - Article ID 925757
  • - Research Article

3D Bioprinting of Carboxymethylated-Periodate Oxidized Nanocellulose Constructs for Wound Dressing Applications

Adam Rees | Lydia C. Powell | ... | David W. Thomas
  • Special Issue
  • - Volume 2015
  • - Article ID 871218
  • - Research Article

Hyaluronic Acid Based Hydrogels for Regenerative Medicine Applications

Assunta Borzacchiello | Luisa Russo | ... | Luigi Ambrosio
  • Special Issue
  • - Volume 2015
  • - Article ID 571816
  • - Research Article

Preparation, Optimization, and Screening of the Effect of Processing Variables on Agar Nanospheres Loaded with Bupropion HCl by a D-Optimal Design

Jaleh Varshosaz | Mohammad Reza Zaki | ... | Jaafar Banoozadeh
  • Special Issue
  • - Volume 2015
  • - Article ID 874316
  • - Research Article

Comparison and Characterisation of Regenerated Chitosan from 1-Butyl-3-methylimidazolium Chloride and Chitosan from Crab Shells

Saniyat Islam | Lyndon Arnold | Rajiv Padhye
  • Special Issue
  • - Volume 2015
  • - Article ID 959175
  • - Review Article

Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy

Saji Uthaman | Sang Joon Lee | ... | In-Kyu Park
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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