BioMed Research International

Chronic Pain: New Insights in Molecular and Cellular Mechanisms


Publishing date
03 Oct 2014
Status
Published
Submission deadline
16 May 2014

Lead Editor

1Department of Experimental Medicine, Division of Pharmacology, Second University of Naples, 80138 Naples, Italy

2Wolfson Centre for Age-Related Diseases, Wolfson Wing Hodgkin Building, Guy's Campus, London SE1 9RT, UK

3Department of Pharmacological and Physiological Science, Saint Louis University School of Medicine, 1402 South Grand Avenue, Saint Louis, MO 63104, USA

4Department of Pharmacology of Pain, Institute of Pharmacology, Polish Academy of Sciences, Ulica Smętna 12, 31-343 Krakow, Poland


Chronic Pain: New Insights in Molecular and Cellular Mechanisms

Description

Chronic pain such as neuropathic pain, osteoarthritic pain, or abnormal pain associated with neurological diseases represents a debilitating condition which strongly affects the quality of life of patients. The mechanisms at the basis of the induction and maintenance of chronic pain are still poorly understood. Thus, an appropriate therapy for chronic pain is not yet available and there are many failures in treatments. Recent evidence suggests a role for central and peripheral immune cells (microglia, macrophages, astrocytes, mast cells, and T cells) in the initiation of peripheral and central sensitization. They mediate the plastic changes occurring within pain pathways that result in sensory dysfunctions and behavioral correlates, such as thermal/mechanical hyperalgesia and tactile allodynia which is a painful sensation after innocuous stimuli.

We invite contributions to this special issue in the form of original research articles as well as review articles. Potential topics include, but are not limited to:

  • Further understanding of the molecular and cellular mechanisms which underlie chronic pain
  • Development of new therapeutic strategies and the evaluation of outcomes
  • The new tools to manipulate pharmacologically neuroglia communication at ganglionic, spinal, and supraspinal levels

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/neuroscience/cp/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 676725
  • - Editorial

Chronic Pain: New Insights in Molecular and Cellular Mechanisms

Livio Luongo | Marzia Malcangio | ... | Katarzyna Starowicz
  • Special Issue
  • - Volume 2015
  • - Article ID 894732
  • - Research Article

Delay of Morphine Tolerance by Palmitoylethanolamide

Lorenzo Di Cesare Mannelli | Francesca Corti | ... | Carla Ghelardini
  • Special Issue
  • - Volume 2015
  • - Article ID 301292
  • - Research Article

Prokineticin 2 Upregulation in the Peripheral Nervous System Has a Major Role in Triggering and Maintaining Neuropathic Pain in the Chronic Constriction Injury Model

Roberta Lattanzi | Daniela Maftei | ... | Lucia Negri
  • Special Issue
  • - Volume 2015
  • - Article ID 905906
  • - Research Article

D-Aspartate Modulates Nociceptive-Specific Neuron Activity and Pain Threshold in Inflammatory and Neuropathic Pain Condition in Mice

Serena Boccella | Valentina Vacca | ... | Alessandro Usiello
  • Special Issue
  • - Volume 2015
  • - Article ID 394257
  • - Review Article

mTOR Kinase: A Possible Pharmacological Target in the Management of Chronic Pain

Lucia Lisi | Paola Aceto | ... | Cinzia Dello Russo
  • Special Issue
  • - Volume 2014
  • - Article ID 498410
  • - Research Article

Proteomic Identification of Altered Cerebral Proteins in the Complex Regional Pain Syndrome Animal Model

Francis Sahngun Nahm | Zee-Yong Park | ... | Pyung Bok Lee
  • Special Issue
  • - Volume 2014
  • - Article ID 495789
  • - Review Article

The Purinergic System and Glial Cells: Emerging Costars in Nociception

Giulia Magni | Stefania Ceruti
  • Special Issue
  • - Volume 2014
  • - Article ID 762930
  • - Research Article

Minocycline Enhances the Effectiveness of Nociceptin/Orphanin FQ during Neuropathic Pain

Katarzyna Popiolek-Barczyk | Ewelina Rojewska | ... | Joanna Mika
  • Special Issue
  • - Volume 2014
  • - Article ID 982121
  • - Research Article

Remote Dose-Dependent Effects of Dry Needling at Distant Myofascial Trigger Spots of Rabbit Skeletal Muscles on Reduction of Substance P Levels of Proximal Muscle and Spinal Cords

Yueh-Ling Hsieh | Chen-Chia Yang | ... | Chang-Zern Hong
  • Special Issue
  • - Volume 2014
  • - Article ID 686908
  • - Research Article

Alterations in the Anandamide Metabolism in the Development of Neuropathic Pain

Natalia Malek | Mateusz Kucharczyk | Katarzyna Starowicz
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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