BioMed Research International

Multimorbidity: Epidemiology and Models of Care


Publishing date
04 Mar 2016
Status
Published
Submission deadline
16 Oct 2015

1University of Brescia, Brescia, Italy

2Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands

3Aragon Health Sciences Institute (IACS), Aragon, Spain

4Università Cattolica del Sacro Cuore, Roma, Italy


Multimorbidity: Epidemiology and Models of Care

Description

Over the last century, chronic health problems have replaced infectious diseases as the dominant health care burden. Multimorbidity, the cooccurrence of multiple chronic diseases in the same person, has been defined as the “most common chronic condition,” and its prevalence progressively increases with age, affecting more than 60% of people aged 65 or older. Multimorbidity has a relevant impact on patient’s outcomes and health care costs in both younger and older adults. Compared to those with single conditions, patients with multimorbidity are more likely to die prematurely, be admitted to hospital, have poorer quality of life, and receive polypharmacy.

Despite the increasing interest of the researchers in this field, there is still a remarkable gap between the harmful impact of multimorbidity at the individual and societal level and the amount of scientific and clinical research devoted to this topic. Current knowledge on multimorbidity can be summarized as follows: (1) multimorbidity affects more than half of older persons; (2) the prevalence increases with age, in women, and in people from lower social classes; (3) very little is known about risk factors for multimorbidity, genetic background, biological causes (such as cholesterol, blood pressure, or obesity level), life styles (such as smoking, drinking, nutrition, or physical activity), environmental factors (air pollution and social environment), or the effect of new diseases by itself; (4) functional impairment, poor quality of life, and high health care utilization and costs are major consequences of multimorbidity; and (5) data are insufficient and not integrated to provide scientific basis for evidence-based care of patients affected by multimorbidity.

Patients with multimorbidity have the most complex health needs but, due to the current disease-oriented approach in healthcare, they face a highly fragmented care that leads to incomplete, inefficient, ineffective, and even potentially harmful interventions. Complexity of care in patients with multimorbidity requires the involvement of a large number of healthcare providers and resources. While there are examples of integrated care programs for chronic diseases implemented in relatively small populations, there are no widely accepted care models for multimorbidity.

We invite investigators to contribute original research articles as well as review articles that seek to address epidemiology of multimorbidity both in the general population and in clinical settings. A particular interest will be given to papers exploring causes of multimorbidity and exploring the prevalence, type, and impact of the presence of multiple cooccurring diseases in important chronic index diseases. Evidence about different models of care for persons with multimorbidity will also be welcomed.

Potential topics include, but are not limited to:

  • Basic research articles especially covering modelling of multimorbidities
  • Genetics and genomics in multimorbidity
  • Development of multimorbidity in disease-free populations
  • Common risk factors for multimorbidity
  • Clustering of chronic diseases
  • Models of care for persons affected by multimorbidity in different settings, especially in primary care
  • Health care utilization and medical costs
  • Ethical aspects of multimorbidity treatment
  • Design of future studies on multimorbidity and its main outcomes

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 7029027
  • - Editorial

Multimorbidity: Epidemiology and Models of Care

A. Marengoni | R. J. F. Melis | ... | G. Onder
  • Special Issue
  • - Volume 2016
  • - Article ID 7845438
  • - Research Article

Different Multimorbidity Measures Result in Varying Estimated Levels of Physical Quality of Life in Individuals with Multimorbidity: A Cross-Sectional Study in the General Population

Aline Ramond-Roquin | Jeannie Haggerty | ... | Martin Fortin
  • Special Issue
  • - Volume 2016
  • - Article ID 6582487
  • - Research Article

Development and Validation of a Questionnaire to Assess Multimorbidity in Primary Care: An Indian Experience

Sanghamitra Pati | Mohammad Akhtar Hussain | ... | Marjan van den Akker
  • Special Issue
  • - Volume 2016
  • - Article ID 8745670
  • - Research Article

Deconstructing Complex Multimorbidity in the Very Old: Findings from the Newcastle 85+ Study

Joanna Collerton | Carol Jagger | ... | Thomas B. L. Kirkwood
  • Special Issue
  • - Volume 2016
  • - Article ID 9053578
  • - Research Article

Disease Combinations Associated with Physical Activity Identified: The SMILE Cohort Study

Sarah Dörenkamp | Ilse Mesters | ... | Rob de Bie
  • Special Issue
  • - Volume 2015
  • - Article ID 718701
  • - Research Article

Cognitive Impairment, Depression, and Cooccurrence of Both among the Elderly in Panama: Differential Associations with Multimorbidity and Functional Limitations

Alcibiades E. Villarreal | Shantal Grajales | ... | Panama Aging Research Initiative
  • Special Issue
  • - Volume 2015
  • - Article ID 965025
  • - Research Article

Defining Multimorbidity: From English to Portuguese Using a Delphi Technique

Filipe Prazeres | Luiz Miguel Santiago | José Augusto Simões
BioMed Research International
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Acceptance rate31%
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CiteScore3.600
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