BioMed Research International

Muscular Dystrophy: Disease Mechanisms and Therapies


Status
Published

1The George Washington University, Washington, USA

2Miami Children’s Hospital, Miami, USA

3University of Alberta, Edmonton, Canada

4Food and Drug Administration, Bethesda, USA


Muscular Dystrophy: Disease Mechanisms and Therapies

Description

In this special issue, we intend to invite researchers to submit original research and review articles on exploring molecular mechanisms and targeted therapy of muscular dystrophy. Studies may involve molecular mechanisms involved in development and treatment of diseases which is often not known and needs more research.

More specifically, this issue will give insight into cellular and molecular mechanism, activation of signaling pathways, how activation of these pathways causes muscle dysfunction, and subsequent disease symptoms. In addition, targeted therapeutic interventions and actions of therapies will be considered.

Potential topics include, but are not limited to:

  • Disease mechanism of muscular dystrophies
  • Molecular mechanisms regulating age-associated muscle wasting and the physiopathology of muscular dystrophies, including the contribution of inflammation and fibrosis to dystrophy progression
  • Animal models of muscle pathologies or diseases
  • New emerging areas of research including new paths for gene and stem cell-based therapeutic strategies for muscular dystrophies
  • Antisense therapy approaches to suppress or eliminate the diseases using DNA-like molecules

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 843743
  • - Research Article

Tyrosine 705 Phosphorylation of STAT3 Is Associated with Phenotype Severity in TGFβ1 Transgenic Mice

Eleonora Guadagnin | Jigna Narola | ... | Yi-Wen Chen
  • Special Issue
  • - Volume 2015
  • - Article ID 891972
  • - Research Article

Systemic Inflammation in Duchenne Muscular Dystrophy: Association with Muscle Function and Nutritional Status

Oriana del Rocío Cruz-Guzmán | Maricela Rodríguez-Cruz | Rosa Elena Escobar Cedillo
  • Special Issue
  • - Volume 2015
  • - Article ID 594751
  • - Research Article

Primary Murine Myotubes as a Model for Investigating Muscular Dystrophy

Natalia Smolina | Anna Kostareva | ... | Thomas Sejersen
  • Special Issue
  • - Volume 2015
  • - Article ID 456348
  • - Editorial

Muscular Dystrophy: Disease Mechanisms and Therapies

Sachchida Nand Pandey | Akanchha Kesari | ... | Gouri Shankar Pandey
  • Special Issue
  • - Volume 2015
  • - Article ID 635792
  • - Review Article

Genetic Engineering of Dystroglycan in Animal Models of Muscular Dystrophy

Francesca Sciandra | Maria Giulia Bigotti | ... | Andrea Brancaccio
  • Special Issue
  • - Volume 2015
  • - Article ID 387090
  • - Research Article

Transcriptional Pathways Associated with Skeletal Muscle Changes after Spinal Cord Injury and Treadmill Locomotor Training

Celine Baligand | Yi-Wen Chen | ... | Krista Vandenborne
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
 Submit