BioMed Research International

Bioinformatics, Experimental and Computational Biology for Personalized Medicine in Chronic Diseases 2021


Publishing date
01 Jun 2022
Status
Closed
Submission deadline
14 Jan 2022

Lead Editor

1Shanghai University, Shanghai, China

2Deakin University, Melbourne, Australia

3Guangxi Medical University, Nanning, China

4Tongji University School of Medicine, Shanghai, China

5Imperial College London, London, UK

This issue is now closed for submissions.
More articles will be published in the near future.

Bioinformatics, Experimental and Computational Biology for Personalized Medicine in Chronic Diseases 2021

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Chronic diseases such as diabetes, cancer, and dry eye disease can become epidemics which eventually threaten human health. The primary reason for this is our inability to detect, diagnose, and treat these diseases. The number of patients with these chronic diseases is increasing rapidly worldwide, and 75% and 85% of the deaths are caused by these diseases in the USA and China, respectively. This accounts for up to 70% of the total disease burden of these countries. In the future, chronic diseases including cardiovascular and cerebrovascular diseases, malignant tumours, and diabetes are very likely to rise.

In the past two decades, with the rapid development of such techniques as high-throughput sequencing, gene editing, and immunotherapy, as well as the discovery of related key genes or pathways in chronic diseases, increasingly in-depth studies of chronic diseases biology have been spurred at the genetic and genomic levels. This has led to better targeted and personalized healthcare solutions for patients. However, this poses a huge challenge for the integration, utilization, and analysis of all the accompanying components.

In this Special Issue, we invite authors to contribute original research articles or reviews for the current problems in these areas.

Potential topics include but are not limited to the following:

  • Discovery of new targets or biomarkers, new diagnostic therapeutic agents, and active targeting agents
  • Protein function and structure analysis and prediction
  • Modification site analysis and identification in protein, DNA, and RNA
  • Clinical data analysis using artificial intelligent techniques
  • Drug target discovery and targeted drug design
  • Personalized therapy based on artificial intelligent techniques
  • NMR spectroscopy, X-ray cryptography, 3D structures of target proteins/RNA/DNA
  • Disease prediction based on Artificial Intelligence

Articles

  • Special Issue
  • - Volume 2022
  • - Article ID 4304419
  • - Research Article

Tex264 Binding to SNX27 Regulates Itgα5 Receptor Membrane Recycling and Affects Cell Migration

Xiao-hui Xu | Qian-wen Yang | ... | Zhao-huan Zhang
  • Special Issue
  • - Volume 2022
  • - Article ID 4792374
  • - Research Article

Experimental Study of Potential CD8+ Trivalent Synthetic Peptides for Liver Cancer Vaccine Development Using Sprague Dawley Rat Models

Sidra Zafar | Baogang Bai | ... | Amjad Ali
  • Special Issue
  • - Volume 2022
  • - Article ID 3206594
  • - Research Article

Causes of Mortality in Korean Patients with Neurodegenerative Dementia

Hyo Geun Choi | Bumjung Park | ... | Miyoung Kim
  • Special Issue
  • - Volume 2022
  • - Article ID 1717784
  • - Research Article

Identification of Key CircRNAs Related to Pulmonary Tuberculosis Based on Bioinformatics Analysis

Qin Yuan | Zilu Wen | ... | Fuxue Chen
  • Special Issue
  • - Volume 2021
  • - Article ID 2396008
  • - Research Article

Analgesic Effects of Different κ-Receptor Agonists Used in Daytime Laparoscopic Cholecystectomy

Wanjun Zhou | Jiawu Wang | ... | Yanhu Xie
  • Special Issue
  • - Volume 2021
  • - Article ID 3654660
  • - Research Article

Target Deconvolution of Fenofibrate in Nonalcoholic Fatty Liver Disease Using Bioinformatics Analysis

Ali Mahmoudi | Alexandra E. Butler | ... | Amirhossein Sahebkar
  • Special Issue
  • - Volume 2021
  • - Article ID 4989297
  • - Research Article

Deep Learning for Accurate Segmentation of Venous Thrombus from Black-Blood Magnetic Resonance Images: A Multicenter Study

Chuanqi Sun | Xiangyu Xiong | ... | Guoxi Xie
  • Special Issue
  • - Volume 2021
  • - Article ID 7739628
  • - Research Article

Comparison of Curative Complications between Mammotome-Assisted Minimally Invasive Resection and Conventional Open Resection for Breast Neoplasm: A Retrospective Clinical Study

Rui Li | Jingyan Li | ... | Ning Zhu
  • Special Issue
  • - Volume 2021
  • - Article ID 7251119
  • - Research Article

A Bioinformatics Approach for the Prediction of Immunogenic Properties and Structure of the SARS-COV-2 B.1.617.1 Variant Spike Protein

Vijay Kumar Srivastava | Sanket Kaushik | ... | Anupam Jyoti
  • Special Issue
  • - Volume 2021
  • - Article ID 4982227
  • - Research Article

Lineage Contribution of PDGFRα-Expressing Cells in the Developing Mouse Eye

Deyi Zhuo | Yumei Diao | ... | Liqiang Wang
BioMed Research International
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Article of the Year Award: Outstanding research contributions of 2021, as selected by our Chief Editors. Read the winning articles.