The world of implant dentistry is experiencing the effects of a real revolution. Techniques such as the placement of dental implants in post-extraction sockets and immediate prosthetic loading are established and widespread. These surgical and prosthetic techniques allow to reduce the time and costs of implant-prosthetic treatment, and are therefore welcome by patients; however, they may represent a risk, especially where it is not possible to obtain an adequate primary stabilization of the implant, due to insufficient bone quantity and quality.

In order to reduce the risks related to the placement of implants in post-extraction sockets and to the immediate prosthetic loading, implant manufacturers have introduced into the market fixtures with specific macrotopographies, designed to increase primary stability, and with surfaces characterised by peculiar micro- and nanotopographies, able to accelerate the processes of bone healing and the biological integration of the implant.

At the same time, the impact of digital technologies is changing the world of Implant Dentistry. Intraoral scanners (IOS) and cone beam computed tomography (CBCT), software for guided implant placement and computer-assisted-design/ computer-assisted manufacturing (CAD/ CAM), new aesthetic materials (zirconia, lithium disilicate, ceramics), milling machines and 3D printers are radically transforming the profession of the surgeon and the prosthodontist.

The aim of this Special Issue is to collate high quality, original research articles, as well as review articles, with a focus on these new materials and technologies.

Potential topics include but are not limited to the following:

• New implant macrotopographies and their effects on implant stability: clinical studies with short- to long-term follow-up
• New implant micro- and nano-topographies and their effects on osseointegration: in vitro studies on cell cultures, in vivo animal histologic/ histomorphometric studies, in vivo human histologic/ histomorphometric studies, and clinical studies with short- to long-term follow-up
• The use of digital technologies (IOS, CBCT, guided surgery) in implant dentistry: in vitro studies, clinical studies with short- to long-term follow-up
• The use of CAD/ CAM software and aesthetic materials (zirconia, lithium disilicate, ceramics) for the restoration of dental implants: in vitro studies, clinical studies with short- to long-term follow-up