BioMed Research International

Natural Killer Cells in Healthy and Diseased Subjects


Publishing date
01 Jul 2011
Status
Published
Submission deadline
01 Jan 2011

1Istituto G. Gaslini, Genova, Italy

2Receptor Cell Biology Section, Laboratory of Immunogenetics, NIAID/NIH, Rockville, MD, USA


Natural Killer Cells in Healthy and Diseased Subjects

Description

The interest of this topic arises from the huge amount of data regarding both inhibitory and activating NK receptors and their ligands gathered in the last 15 years and the use of this information for clinical purposes. Nowadays, it is clear that NK cell receptors evolved in a highly dynamic fashion, primarily driven by the necessity to deal with a large variety of pathogens and to recognize properties of cells characteristic of tumor transformation.

Thus, the aim and scope of this special issue will be to analyze the expression and function of both inhibitory and activating NK receptors and their ligands and the mechanisms involved in the molecular regulation of innate immunity and in the NK-mediated regulation of adaptive cellular responses. A particular emphasis will be dedicated to NK cells and diseases. Potential topics include but are not limited to:

  • NK receptors/ligands expression and their regulation in NK cells and their precursors
  • Structural/functional analysis of NK receptor/ligand interactions
  • Regulation of DC maturation
  • Regulation of adaptive immune responses
  • NK cell responses to cancer/pathogens
  • KIR/HLA interactions and pathogens immunity
  • Role of pathogen-produced proteins
  • Role of lymphokines
  • Role of miRNAs
  • Animal models to study NK cells and diseases

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jbb/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 795251
  • - Editorial

Natural Killer Cells in Healthy and Diseased Subjects

Roberto Biassoni | John E. Coligan | Lorenzo Moretta
  • Special Issue
  • - Volume 2011
  • - Article ID 152430
  • - Review Article

Involvement of Activating NK Cell Receptors and Their Modulation in Pathogen Immunity

Francesco Marras | Federica Bozzano | Andrea De Maria
  • Special Issue
  • - Volume 2011
  • - Article ID 724607
  • - Review Article

How the Virus Outsmarts the Host: Function and Structure of Cytomegalovirus MHC-I-Like Molecules in the Evasion of Natural Killer Cell Surveillance

Maria Jamela Revilleza | Rui Wang | ... | David H. Margulies
  • Special Issue
  • - Volume 2011
  • - Article ID 861920
  • - Review Article

Role of Common-Gamma Chain Cytokines in NK Cell Development and Function: Perspectives for Immunotherapy

Raffaella Meazza | Bruno Azzarone | ... | Silvano Ferrini
  • Special Issue
  • - Volume 2011
  • - Article ID 348530
  • - Review Article

Potential Role of NK Cells in the Pathogenesis of Inflammatory Bowel Disease

Praveen K. Yadav | Chi Chen | Zhanju Liu
  • Special Issue
  • - Volume 2011
  • - Article ID 248317
  • - Review Article

NK Cells and Psoriasis

Sinéad Dunphy | Clair M. Gardiner
  • Special Issue
  • - Volume 2011
  • - Article ID 379123
  • - Review Article

Clinical Cancer Therapy by NK Cells via Antibody-Dependent Cell-Mediated Cytotoxicity

Kory L. Alderson | Paul M. Sondel
  • Special Issue
  • - Volume 2011
  • - Article ID 641702
  • - Review Article

The Impact of Ly49-NK Cell-Dependent Recognition of MCMV Infection on Innate and Adaptive Immune Responses

Michal Pyzik | Eve-Marie Gendron-Pontbriand | Silvia M. Vidal
  • Special Issue
  • - Volume 2011
  • - Article ID 298348
  • - Review Article

KIR/HLA Interactions and Pathogen Immunity

Khaleel M. Jamil | Salim I. Khakoo
  • Special Issue
  • - Volume 2011
  • - Article ID 203628
  • - Review Article

The Structural Basis of Ligand Recognition by Natural Killer Cell Receptors

M. Gordon Joyce | Peter D. Sun
BioMed Research International
 Journal metrics
Acceptance rate30%
Submission to final decision83 days
Acceptance to publication45 days
CiteScore2.410
Impact Factor2.197
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