BioMed Research International

Cardiac Arrest and Cardiopulmonary Resuscitation: Starting from Basic Science and Bioengineering Research to Improve Resuscitation Outcome


Status
Published

1Mario Negri Institute for Pharmacological Research, Milan, Italy

2University Affiliated Hospital “Santa Maria degli Angeli”, Pordenone, Italy

3Third Military Medical University and Chongqing University, Chongqing, China


Cardiac Arrest and Cardiopulmonary Resuscitation: Starting from Basic Science and Bioengineering Research to Improve Resuscitation Outcome

Description

Only in the West, as many as 400,000 Americans and 300,000 Europeans sustain cardiac arrest each year. Though the initial success of cardiopulmonary resuscitation (CPR) is approximately 39%, the majority of victims die within 72 hours, due to the postresuscitation syndrome. Morbidity and mortality after successful CPR largely depend on recovery of neurologic function. As many as 30% of survivors of cardiac arrest, in fact, manifest permanent brain damage and in some instances only 2–12% of resuscitated patients have been discharged from hospital without neurological dysfunction. The mechanisms responsible for this poor outcome are not well understood, although several events related to the systemic ischemia that follows onset of cardiac arrest as well as the reintroduction of oxygenated blood after return of spontaneous circulation have been described. Knowledge and understanding of these conditions have led to the development of animal models, successful therapies, and novel tools to characterize these clinical conditions and provide better care to patients.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand mechanisms contributing to cardiac arrest and CPR outcome, the development of new interventional strategies to improve resuscitation and post resuscitation survival with good functional outcome, new approach for evaluation and prediction of outcome, and different CPR training methodologies. We are particularly interested in articles directed to promote, share, and disseminate new experimental and clinical advances on resuscitation and postresuscitation care and CPR training. Specific attention is dedicated to evidence from experimental and clinical trials, controversial topics on resuscitation, and gold standard and experimental resuscitation and postresuscitation treatments and interventions.

Potential topics include, but are not limited to:

  • Physiopathology of cardiac arrest, CPR, and postresuscitation syndrome
  • Priority of intervention during CPR
  • Quality of resuscitation
  • Qechanical supports
  • New defibrillation strategies
  • Prevention of organ damage
  • Postresuscitation care
  • Hypothermia
  • New pharmacological treatments
  • Outcome of CPR and survival
  • Organization models and integrated care systems
  • Translational research
  • Impact of CPR taining in the school

Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 737542
  • - Editorial

Cardiac Arrest and Cardiopulmonary Resuscitation: Starting from Basic Science and Bioengineering Research to Improve Resuscitation Outcome

Giuseppe Ristagno | Tommaso Pellis | Yongqin Li
  • Special Issue
  • - Volume 2014
  • - Article ID 610591
  • - Research Article

Effect of Engaging Trainees by Assessing Peer Performance: A Randomised Controlled Trial Using Simulated Patient Scenarios

Charlotte Loumann Krogh | Charlotte Ringsted | ... | Lars Konge
  • Special Issue
  • - Volume 2014
  • - Article ID 872470
  • - Research Article

A Reliable Method for Rhythm Analysis during Cardiopulmonary Resuscitation

U. Ayala | U. Irusta | ... | D. González-Otero
  • Special Issue
  • - Volume 2014
  • - Article ID 140438
  • - Research Article

Removal of Cardiopulmonary Resuscitation Artifacts with an Enhanced Adaptive Filtering Method: An Experimental Trial

Yushun Gong | Tao Yu | ... | Yongqin Li
  • Special Issue
  • - Volume 2014
  • - Article ID 376871
  • - Review Article

Oxygenation, Ventilation, and Airway Management in Out-of-Hospital Cardiac Arrest: A Review

Tomas Henlin | Pavel Michalek | ... | Milos Dobias
  • Special Issue
  • - Volume 2014
  • - Article ID 192769
  • - Research Article

Impaired Cerebral Mitochondrial Oxidative Phosphorylation Function in a Rat Model of Ventricular Fibrillation and Cardiopulmonary Resuscitation

Jun Jiang | Xiangshao Fang | ... | Zitong Huang
  • Special Issue
  • - Volume 2014
  • - Article ID 276965
  • - Research Article

Towards the Automated Analysis and Database Development of Defibrillator Data from Cardiac Arrest

Trygve Eftestøl | Lawrence D. Sherman
  • Special Issue
  • - Volume 2014
  • - Article ID 386010
  • - Review Article

Rhythm Analysis during Cardiopulmonary Resuscitation: Past, Present, and Future

Sofia Ruiz de Gauna | Unai Irusta | ... | Trygve Eftestøl
  • Special Issue
  • - Volume 2013
  • - Article ID 564501
  • - Research Article

Outcome of Prolonged Ventricular Fibrillation and CPR in a Rat Model of Chronic Ischemic Left Ventricular Dysfunction

Xiangshao Fang | Lei Huang | ... | Wanchun Tang
  • Special Issue
  • - Volume 2013
  • - Article ID 312137
  • - Research Article

Improved Early Postresuscitation EEG Activity for Animals Treated with Hypothermia Predicted 96 hr Neurological Outcome and Survival in a Rat Model of Cardiac Arrest

Bihua Chen | Feng-Qing Song | ... | Yongqin Li
BioMed Research International
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Acceptance rate31%
Submission to final decision67 days
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CiteScore3.600
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