Inflammatory reaction in the central nervous system (CNS) is now recognized to be a feature of all neurological disorders. In neurological degenerative diseases, such as multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, and chronic neuropathic pain, there is prominent infiltration of various leukocyte subsets into the CNS or there is intense activation of microglia with resultant elevation of many inflammatory mediators within the CNS. For acute critical CNS diseases, such as delayed deterioration associated with vasospasm after subarachnoid hemorrhage (SAH), ischemic stroke, spontaneous intracerebral hemorrhage (ICH), and traumatic brain injury (TBI), recent further evidence shows that inflammation may be a potential target for therapy. Inflammation has become a promising area of research for new treatments. Knowledge and understanding of these conditions have led to the development of animal models, successful therapies, and novel tools to characterize these clinical conditions and provide better care to patients.

We invite authors to submit original research and review articles that will stimulate the continuing efforts to understand the molecular pathology underlying inflammatory neurological disease, the development of strategies to treat these conditions, and the evaluation of outcomes. We are particularly interested in articles describing the new modalities for clinical characterization of inflammatory neurological disease and measuring outcomes from treatment trials, advances in molecular diagnostics, new insights into inflammatory neurological disease using animal models, and current concepts in the treatment of inflammatory neurological disease. Potential topics include, but are not limited to:

• Recent developments in inflammatory neurological disease research, especially on ischemic/hemorrhagic stroke patients
• Identifying potential biomarkers/correlates of inflammation to predictive stroke in patients with immunocompromised
• Latest technologies for clinical evaluation and measuring outcomes, especially neural inflammation in neuroimage findings
• New cellular and animal models to test and understand inflammatory neurological disease
• Recent advances in CNS drug delivery

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/neuroscience/irnd/ according to the following timetable: