BioMed Research International

Therapeutic Strategies against Inflammation-Related Diseases: Molecular Mechanisms and Clinical Applications

Publishing date
01 May 2015
Submission deadline
12 Dec 2014

Lead Editor

1Fu Jen Catholic University, New Taipei City, Taiwan

2China Medical University, Taichung, Taiwan

3University of Cincinnati, Cincinnati, USA

Therapeutic Strategies against Inflammation-Related Diseases: Molecular Mechanisms and Clinical Applications


Inflammation is a complicated cellular and molecular process of vascular tissues response to harmful stimuli. It is a protective mechanism by the host to remove the harmful stimuli, initiating the healing process to promote tissue recovery. However, inadequate or chronic inflammation can lead to a lot of diseases, such as atherosclerosis, cardiac valvular disease, cancer, respiratory diseases, and rheumatoid arthritis. Among these, cardiovascular diseases (CVDs) and cancer are the major leading causes of death worldwide. Recent advances in biology and biochemistry of these two diseases have introduced new technologies to study the molecular mechanisms and pathogenesis underlying their pathology. Knowledge and understanding of these conditions have led to the development of some successful therapies, which may provide better care to these patients.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the molecular mechanisms underlying CVD- and cancer-associated inflammations and the development of novel strategies to treat these diseases. We are particularly interested in articles discussing new insights, technologies, and concepts that advance our understanding in pathogenesis, as well as novel strategies to prevent or treat these diseases using small molecules, siRNA, proteins, or other molecular approaches.

Potential topics include, but are not limited to:

  • Mechanisms in inflammation-related diseases, especially in CVD- and tumor-associated inflammation
  • Latest technologies or animal models for the diseases
  • Novel natural or synthetic compounds implicated to prevent or treat inflammation-related diseases
  • Structure-activity relationship of the novel agents
  • Recent advances in drug delivery for these diseases


  • Special Issue
  • - Volume 2015
  • - Article ID 102021
  • - Research Article

Huangqin-Tang Ameliorates TNBS-Induced Colitis by Regulating Effector and Regulatory CD4+ T Cells

Ying Zou | Wen-Yang Li | ... | Xue-Bao Zheng
  • Special Issue
  • - Volume 2015
  • - Article ID 382730
  • - Editorial

Therapeutic Strategies against Inflammation-Related Diseases: Molecular Mechanisms and Clinical Applications

Wen-Bin Wu | Wei-Chien Huang
  • Special Issue
  • - Volume 2015
  • - Article ID 518284
  • - Research Article

Prognosis Relevance of Serum Cytokines in Pancreatic Cancer

Carolina Torres | Ana Linares | ... | Sonia Perales
  • Special Issue
  • - Volume 2015
  • - Article ID 862391
  • - Research Article

Flax Fiber Hydrophobic Extract Inhibits Human Skin Cells Inflammation and Causes Remodeling of Extracellular Matrix and Wound Closure Activation

Monika Styrczewska | Anna Kostyn | ... | Jan Szopa
  • Special Issue
  • - Volume 2015
  • - Article ID 689614
  • - Research Article

Interleukin-27 Protects Cardiomyocyte-Like H9c2 Cells against Metabolic Syndrome: Role of STAT3 Signaling

Wei-Lian Phan | Yu-Tzu Huang | Ming-Chieh Ma
  • Special Issue
  • - Volume 2014
  • - Article ID 407518
  • - Review Article

The Characteristics of Thrombin in Osteoarthritic Pathogenesis and Treatment

Pei-Yu Chou | Chen-Ming Su | ... | Chih-Hsin Tang
BioMed Research International
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