The development of computer-aided design and manufacturing (CAD/CAM) for virtual surgical planning (VSP) has enabled preoperative planning in three dimensions. In addition, the virtual surgical plan can be modelled and the outcomes analyzed for longitudinal form and function. Since the surgical plan is developed in a virtual environment, an unlimited number of iterations can be analyzed until the desired outcome is achieved. These new technologies have opened new horizons for all types of surgeries in the head and neck districts and they can provide a wide range of applications varying from facial and cranial bone defects, bone repositioning, microsurgery, oral surgery, or facial contouring.

In addition to virtual planning, this technology enables the manufacturing of guides, implants, and models for intraoperative use. These can be used to make precise demolitions or reconstruction and to minimise patients’ biological cost, shorten surgery duration, and generally achieve better results.

In this Special Issue, we would like to gather the experiences of different colleagues coming from different surgical branches in order to create an account of the state of the art in computer planning and computer manufacturing in the head and neck district. Original research and review articles are welcome.

Potential topics include but are not limited to the following:

• Maxillofacial surgery
• Reconstructive facial surgery
• Facial bone contouring
• CAD/CAM implants
• Computer aided surgery
• Customised implants
• Facial aesthetics
• Neurosurgery
• Cranioplasty