BioMed Research International

Transmission of Information in Neoplasia by Extracellular Vesicles


Status
Published

Lead Editor

1Roseman University, Las Vegas, USA

2Dresden University of Technology, Dresden, Germany

3Yale University, New Haven, USA

4Palermo University, Palermo, Italy


Transmission of Information in Neoplasia by Extracellular Vesicles

Description

While mutations and epigenetic events are thought to be the principal modalities by which tumor cells escape homeostatic controls and acquire the ability to invade and metastasize, accumulating evidence also points to other mechanisms. These include the contribution of cell-cell fusion, extracellular vesicles (e.g., microvesicles and exosomes), and plasma membrane protrusions including cytonemes, tunneling nanotubes, and magnupodia as vehicles for the transfer of information among cancer cells, between cancer and stromal cells, and between cancer cells and the immune system of the host. These provide alternative pathways by which cells can acquire tumorigenic properties and sculpt the tumor microenvironment at both the primary and the metastatic sites.

We invite investigators to contribute original research articles as well as reviews that will help in understanding the contribution of these emerging mechanisms to tumor growth and metastasis.

Potential topics include, but are not limited to:

  • Role of microvesicles/exosomes in carcinogenesis and cancer progression
  • Viruses, proteins, and other agents involved in cell fusion in neoplasia
  • Role of cell fusion in carcinogenesis and cancer progression
  • Tunneling nanotubes and cytoneme-mediated transport
  • Role of plasma membrane protrusions in intercellular communication
  • Exchange of chromatin and organelles between cells

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 289567
  • - Editorial

Transmission of Information in Neoplasia by Extracellular Vesicles

Aurelio Lorico | Denis Corbeil | ... | Riccardo Alessandro
  • Special Issue
  • - Volume 2015
  • - Article ID 634865
  • - Review Article

Breast Cancer-Derived Extracellular Vesicles: Characterization and Contribution to the Metastatic Phenotype

Toni M. Green | Mary L. Alpaugh | ... | Aurelio Lorico
  • Special Issue
  • - Volume 2015
  • - Article ID 454837
  • - Review Article

The Emerging Role of Extracellular Vesicle-Mediated Drug Resistance in Cancers: Implications in Advanced Prostate Cancer

Carolina Soekmadji | Colleen C. Nelson
  • Special Issue
  • - Volume 2015
  • - Article ID 821613
  • - Review Article

Role of Extracellular Vesicles in Hematological Malignancies

Stefania Raimondo | Chiara Corrado | ... | Riccardo Alessandro
  • Special Issue
  • - Volume 2015
  • - Article ID 649161
  • - Review Article

The Role of Extracellular Vesicles: An Epigenetic View of the Cancer Microenvironment

Zhongrun Qian | Qi Shen | ... | Wenbin Zhang
  • Special Issue
  • - Volume 2015
  • - Article ID 152926
  • - Review Article

Extracellular Membrane Vesicles as Vehicles for Brain Cell-to-Cell Interactions in Physiological as well as Pathological Conditions

Gabriella Schiera | Carlo Maria Di Liegro | Italia Di Liegro
  • Special Issue
  • - Volume 2015
  • - Article ID 701390
  • - Research Article

High LIN28A Expressing Ovarian Cancer Cells Secrete Exosomes That Induce Invasion and Migration in HEK293 Cells

Vanessa A. Enriquez | Ellane R. Cleys | ... | Gerrit J. Bouma
  • Special Issue
  • - Volume 2015
  • - Article ID 125807
  • - Review Article

Role of Exosomal Noncoding RNAs in Lung Carcinogenesis

Tao Sun | Bill Kalionis | ... | Wen Gao
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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