BioMed Research International

Aging and Longevity between Genetic Background and Lifestyle Intervention

Publishing date
23 May 2014
Submission deadline
03 Jan 2014

1Department of Biology, Ecology and Earth Science, University of Calabria, 87036 Rende, Italy

2Department of Nutrition Science, University of Alabama at Birmingham, Birmingham, AL 35294, USA

3National Hellenic Research Foundation (N.H.R.F.), Institute of Biology, Medicinal Chemistry and Biotechnology Division of Biological Research & Biotechnology (IBRB), 48 Vas. Constantinou Avenue, 11635 Athens, Greece

Aging and Longevity between Genetic Background and Lifestyle Intervention


The research on the determinants of the age related decline and on the mechanisms that allow to postpone aging and achieve longevity is continuously growing, due to the great interest that modern societies (where the population segment older than 65 is, in most cases, almost one-third of the whole population) have for aging. In particular, the current research has focused on the genetic basis of lifespan modulation and also on the possible interventions (such as interventions on diet) which can modulate the aging phenotype and lifespan. Both approaches have been pursued by studying model organisms (namely, nematodes, drosophila, and mice) and by studying human population cohorts. At this moment we begin to have an idea of the complex mechanisms underlying aging, of the genetic basis of the interindividual differences of the aging phenotype and lifespan, and also of the possible strategies that can be used to postpone the age related physical and cognitive decline.

This issue aims at collecting new data on the field of aging and longevity and at reviewing the most recent researches in the field, in order to give an updated snapshot of the knowledge on the subject and also of the different perspectives where the problem of aging and longevity can be observed from.

Thus we invite researchers to contribute original research articles and updated review articles on the following. Potential topics include, but are not limited to:

  • Aging in model organisms
  • Human aging
  • The biology of physical and cognitive decline
  • The genetic and epigenetic biomarkers of aging
  • Nutrition, healthy aging, and longevity
  • Lifestyle, healthy aging, and longevity
  • Microbiota, healthy aging, and longevity
  • Demography of longevity

Before submission authors should carefully read over the journal’s Author Guidelines which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:

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