BioMed Research International

Renal Transplantation: What Has Changed in Recent Years


Publishing date
01 Dec 2018
Status
Published
Submission deadline
03 Aug 2018

1University of Naples Federico II, Naples, Italy

2University of Padua, Padua, Italy

3Imperial College NHS, London, UK

4Guy's and St. Thomas' NHS Foundation Trust, London, UK

5Hopitaux Universitaire de Geneve, Geneve, Switzerland

6Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands


Renal Transplantation: What Has Changed in Recent Years

Description

The gold standard for ESRD is renal transplantation, a procedure that in 2014 has been performed in almost 80000 patients and in 2016 in over 85000 cases worldwide. The number of renal transplants is always lower than the one of the ESRD patients but the trend is on the rise, because of the improvement in surgical, nephrological, and immunological fields. In the last ten years, in fact, thanks to innovative technologies that help the surgical procedure, the use of newer and safer immunosuppressive drugs, and a better knowledge of the risk factors and the complications that transplant patients develop, there have been greater results in this field.

The first renal transplant dates back to the early 1950s. Since then a lot has changed in the renal transplantation world. Just to show some aspects: the surgical indication has been extended to patients that have never been taken into account for it before; old age patients with many comorbidities nowadays are considered for the donation; we are trying to optimize the use of DCD’s kidneys; preservation’s solutions and techniques, such as dynamic perfusion, have been improved so that ECD can be used with good results; thanks to new drugs and technologies we are forcing the histocompatibility barrier so that transplant between patients with ABO incompatibility or with high level of antibodies is possible; new ways of harvesting from living donors are always less invasive and more precise (laparoscopic and robotic harvesting).

These changes are happening so fast that it is hard to follow all of them.

The aim of this special issue is to show the state of the art of the most recent changes in the renal transplantation world and to know the newest trend that this wonderful and interesting field of medicine and surgery is chasing. For these reasons, we invite investigators to contribute research articles as well as review articles that address these innovations in surgical, nephrological, and immunological field as well as new proposals about renal transplantation.

Potential topics include but are not limited to the following:

  • How to improve the donors’ pool: new horizons for the use of DCD, ECD, and suboptimal and living donors
  • What has changed in the recipients’ selection: the importance of the comorbidity on short and long term results
  • ABO incompatibility, antibodies, and other immunological factors are still a limit in the renal transplantation
  • What has changed in the preservation and harvesting techniques
  • What has changed in the surgical techniques and technologies
  • Newest trend regarding the immunosuppressive drugs
  • New trend in the anaesthetic field and in the perioperative treatments
  • Clinical and instrumental follow-up of renal transplanted patients: how to lead it and which techniques to use in the light of the new knowledge

Articles

  • Special Issue
  • - Volume 2019
  • - Article ID 3618104
  • - Editorial

Renal Transplantation: What Has Changed in Recent Years

Michele Santangelo | Lucrezia Furian | ... | Maria Irene Bellini
  • Special Issue
  • - Volume 2019
  • - Article ID 8572138
  • - Research Article

Influence of Hypoxic Preservation Temperature on Endothelial Cells and Kidney Integrity

Sébastien Giraud | Clara Steichen | ... | Thierry Hauet
  • Special Issue
  • - Volume 2019
  • - Article ID 1729138
  • - Review Article

Donor and Recipient Outcomes following Robotic-Assisted Laparoscopic Living Donor Nephrectomy: A Systematic Review

Massimiliano Creta | Armando Calogero | ... | Nicola Carlomagno
  • Special Issue
  • - Volume 2019
  • - Article ID 4674560
  • - Review Article

Eradication of HCV Infection with the Direct-Acting Antiviral Therapy in Renal Allograft Recipients

Armando Calogero | Evangelista Sagnelli | ... | Caterina Sagnelli
  • Special Issue
  • - Volume 2019
  • - Article ID 7343182
  • - Research Article

Pretransplant Nephrectomy for Large Polycystic Kidneys in ADPKD (Autosomal Dominant Polycystic Kidney Disease) Patients: Is Peritoneal Dialysis Recovery Possible after Surgery?

Giuseppe Ietto | Veronica Raveglia | ... | Giulio Carcano
  • Special Issue
  • - Volume 2019
  • - Article ID 6302153
  • - Research Article

Introducing of the First DCD Kidney Transplantation Program in Poland

Honorata Stadnik | Tomasz Małkiewicz | ... | Marek Karczewski
  • Special Issue
  • - Volume 2019
  • - Article ID 7435248
  • - Research Article

Cold Pulsatile Machine Perfusion versus Static Cold Storage in Kidney Transplantation: A Single Centre Experience

Maria Irene Bellini | Sotiris Charalampidis | ... | Vassilios Papalois
  • Special Issue
  • - Volume 2018
  • - Article ID 9206257
  • - Review Article

Barriers and Advances in Kidney Preservation

C. Steichen | S. Giraud | ... | R. Thuillier
  • Special Issue
  • - Volume 2018
  • - Article ID 7465435
  • - Research Article

The Effect of Modified Biolasol Solution on the Efficacy of Storing Isolated Porcine Kidneys

Aneta Ostróżka-Cieślik | Barbara Dolińska | Florian Ryszka
  • Special Issue
  • - Volume 2018
  • - Article ID 8953581
  • - Clinical Study

Eradication of HCV in Renal Transplant Recipients and Its Effects on Quality of Life

Massimo Sabbatini | Ivana Capuano | ... | Filomena Morisco
BioMed Research International
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Acceptance rate30%
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CiteScore2.410
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