BioMed Research International

A Novel Role for Extracellular Vesicles in Cytopathology and New Therapeutic Strategies


Publishing date
01 Aug 2019
Status
Published
Submission deadline
15 Mar 2019

Lead Editor

1Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China

2Oxford Brookes University, Oxford, UK


A Novel Role for Extracellular Vesicles in Cytopathology and New Therapeutic Strategies

Description

Extracellular vesicles (EVs) are nanovesicles enclosing proteins and nucleic acids; they are a newly discovered way by which cells communicate with their neighbours. EVs, including exosomes (φ 30–100 nm) and microvesicles (φ 100–1,000 nm), are generated and released from almost all cell types and are present in almost all biological fluids.

EVs, especially exosomes, have been attracting increased attention both for their role in pathology and their possible use in diagnostic and therapeutic tools. Therefore, it is increasingly crucial to uncover the pathogenic pathways in which EVs may participate and to better use EVs as diagnostic and therapeutic tools for the development of more effective therapies.

The topic of this special issue is the role of EVs in the pathogenesis of a variety of diseases (including cancer, degenerative diseases, rheumatism, and nervous system diseases) and the new therapeutic strategies using EVs (including tissue regeneration, drug delivery, and targeted therapies). Studies using animal or cell culture models to investigate molecular mechanisms will be considered. Special attention will be given to new methods for improving the function of EVs via modularized EVs. This special issue will also cover reports on patients, providing novel mechanistic insights into the underlying pathogenesis or previously unknown aspects that may impact clinical therapy. Review articles are also welcome.

Potential topics include but are not limited to the following:

  • EVs/exosomes in special areas, including rheumatic disease, degenerative disease, nervous system disease, and developmental disease
  • EVs/exosomes in the tumour microenvironment
  • Circulating EVs/exosomes
  • Nanotechnology and EVs/exosomes
  • Gene-based therapies using EVs/exosomes

Articles

  • Special Issue
  • - Volume 2019
  • - Article ID 7137613
  • - Editorial

A Novel Role for Extracellular Vesicles in Cytopathology and New Therapeutic Strategies

Shi-Cong Tao | Shang-Chun Guo | Johnny Collett
  • Special Issue
  • - Volume 2019
  • - Article ID 6458237
  • - Review Article

MSC-Derived Exosomes-Based Therapy for Peripheral Nerve Injury: A Novel Therapeutic Strategy

Ruiqi Dong | Yumei Liu | ... | Ziqiang Zhang
  • Special Issue
  • - Volume 2019
  • - Article ID 3612020
  • - Research Article

Serum Exosomal MicroRNAs Predict Acute Respiratory Distress Syndrome Events in Patients with Severe Community-Acquired Pneumonia

Xu Wu | Chengzhi Wu | ... | Lei Zhu
  • Special Issue
  • - Volume 2019
  • - Article ID 1983131
  • - Review Article

Exosomes in the Repair of Bone Defects: Next-Generation Therapeutic Tools for the Treatment of Nonunion

Jian Lu | Qi-Yang Wang | Jia-Gen Sheng
  • Special Issue
  • - Volume 2019
  • - Article ID 6071308
  • - Research Article

Circulating Exosomes Derived-miR-146a from Systemic Lupus Erythematosus Patients Regulates Senescence of Mesenchymal Stem Cells

Chen Dong | Qiao Zhou | ... | Juan Ji
  • Special Issue
  • - Volume 2019
  • - Article ID 1460572
  • - Review Article

Multiple Roles of Exosomal Long Noncoding RNAs in Cancers

Wenyuan Zhao | Yuanqi Liu | ... | Chaojun Duan
  • Special Issue
  • - Volume 2019
  • - Article ID 4649705
  • - Review Article

Potential Role of Exosomes in Cancer Metastasis

Wenjuan Tian | Shanshan Liu | Burong Li
  • Special Issue
  • - Volume 2019
  • - Article ID 1759697
  • - Research Article

Expression Profiling of Exosomal miRNAs Derived from the Peripheral Blood of Kidney Recipients with DGF Using High-Throughput Sequencing

Junpeng Wang | Xin Li | ... | Tianzhong Yan
  • Special Issue
  • - Volume 2019
  • - Article ID 9258075
  • - Review Article

Noncoding RNAs Act as Tumor-Derived Molecular Components in Inducing Premetastatic Niche Formation

Zhedong Zhang | Jiao Qiao | ... | Shu Li
  • Special Issue
  • - Volume 2019
  • - Article ID 2103943
  • - Review Article

Exosomes Modulate the Viral Replication and Host Immune Responses in HBV Infection

Shuang Li | Shilin Li | ... | Limin Chen
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
 Submit

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.