BioMed Research International

Novel Topics in Inflammatory Bowel Disease


Status
Published

1University of Chicago, Chicago, USA

2Catholic University, Milano, Italy

3Oregon Health & Science University, Portland, USA

4Keio University, Tokyo, Japan


Novel Topics in Inflammatory Bowel Disease

Description

Inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, is a relapsing and remitting condition characterized by chronic inflammation of the digestive tract, which results in various intestinal and extraintestinal symptoms. With the advancement of basic, translational, and clinical research, understanding and management of IBD have greatly progressed. The exact cause of IBD still remains unknown, but research shows that genetic, immunological, and environmental factors play a role in the initiation, perpetuation, and perturbation of the disease process. The imbalance of the gut microbiome has recently been linked to IBD, and fecal microbiota transplantation has emerged as a potential therapy. Clinical management has greatly changed in the past decade by the development of anticytokine-based biologic treatment, and the treatment goals are now to achieve mucosal healing and alter the natural course of the disease. To promote the basic and clinical research field in IBD, we invite investigators to contribute original research articles as well as review articles that will stimulate continuing efforts to understand the mechanisms and management of IBD.

Potential topics include, but are not limited to:

  • Genetics and racial difference
  • Immunology and tolerance
  • Host-microbe interaction and fecal transplantation
  • Novel diagnostic approaches including biomarkers, serology, and imaging modalities
  • Biologic and nonbiologic therapy
  • Therapeutic drug monitoring of biologics and immunomodulators
  • Mucosal Healing
  • Disease related complications including colorectal cancer and its surveillance
  • Therapy related complications including malignancy and infections
  • Surgery and postoperative management

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 8958751
  • - Editorial

Novel Topics in Inflammatory Bowel Disease

Atsushi Sakuraba | Alessandro Armuzzi | ... | Makoto Naganuma
  • Special Issue
  • - Volume 2016
  • - Article ID 5989128
  • - Research Article

Immunohistochemical Studies on Galectin Expression in Colectomised Patients with Ulcerative Colitis

Mattias Block | Johan Mölne | ... | Michael E. Breimer
  • Special Issue
  • - Volume 2015
  • - Article ID 921730
  • - Research Article

Incidence Trends and Geographical Variability of Pediatric Inflammatory Bowel Disease in Slovenia: A Nationwide Study

Darja Urlep | Rok Blagus | Rok Orel
  • Special Issue
  • - Volume 2015
  • - Article ID 416838
  • - Research Article

Genetic Polymorphisms of IL-17F and TRAF3IP2 Could Be Predictive Factors of the Long-Term Effect of Infliximab against Crohn’s Disease

Shigetoshi Urabe | Hajime Isomoto | ... | Kazuhiro Tsukamoto
  • Special Issue
  • - Volume 2015
  • - Article ID 172756
  • - Research Article

Immunohistochemical Expression of Ornithine Decarboxylase, Diamine Oxidase, Putrescine, and Spermine in Normal Canine Enterocolic Mucosa, in Chronic Colitis, and in Colorectal Cancer

Giacomo Rossi | Matteo Cerquetella | ... | Nicolae Manolescu
  • Special Issue
  • - Volume 2015
  • - Article ID 528523
  • - Research Article

Actions of Probiotics on Trinitrobenzenesulfonic Acid-Induced Colitis in Rats

Takahiko Shiina | Takeshi Shima | ... | Yasutake Shimizu
  • Special Issue
  • - Volume 2015
  • - Article ID 359130
  • - Research Article

The Demographic and Clinical Characteristics of Ulcerative Colitis in a Northeast Brazilian Population

Bruno César da Silva | Andre Castro Lyra | ... | Genoile Oliveira Santana
BioMed Research International
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Acceptance rate31%
Submission to final decision67 days
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CiteScore3.600
Impact Factor2.276
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