BioMed Research International

Mercury Toxicity


Publishing date
05 Oct 2012
Status
Published
Submission deadline
06 Apr 2012

1Universidade de Santa Maria, Santa Maria, RS, Brazil

2Department of Pharmacology, Vanderbilt University, Nashville, TN, USA

3Department of Neuroscience, Karolinska Institute, Stockholm, Sweden

4Department of Biochemistry, Federal University of Santa Catarina, Florianópolis, SC, Brazil

5Universidade Federal do Pará, Belém, PA, Brazil


Mercury Toxicity

Description

Mercury (Hg) is one of the most toxic elements in the periodic table. It has been released into the environment for centuries. Nowadays, there are efforts to reduce its anthropogenic use; however, its environmental presence is significant and will persist for a long time. Inorganic Hg can be biotransformed in aquatic sediments to methylmercury (MeHg) that can be biomagnified in the web chain and can attain alarming levels in predatory fish. Consequently, human populations can be exposed to mercury via consumption of fish. The deleterious impact of exposure to Hg during critical phases of brain development is unpredictable, and both experimental and epidemiological data have indicated that it is impossible to establish a nonobservable adverse effect level (NOAEL) for Hg. Furthermore, the exposure to MeHg in adults can cause delayed neurotoxic effects. Thus, the accepted safe daily intakes of MeHg, which are considered without hazards to humans, are possibly above the true NOAEL. As a soft electrophile, MeHg has a strong affinity for soft nucleophiles (thiol and selenol groups). These groups play important biochemical functions in proteins, and the inactivation of thiol- or selenol-containing enzymes can disrupt cell physiology. In this special issue, we invite investigators to contribute original research articles as well as review articles that will stimulate the continuous efforts to understand the molecular mechanisms involved in the toxicology of mercury and its environmental and epidemiological consequences. In effect, the collective analysis of the results obtained in experimental studies with those obtained in the epidemiological studies is expected to provide a more precise assessment of the hazards associated with low-level mercury exposures. Potential topics include, but are not limited to:

  • Molecular, environmental, occupational, and accidental toxicity of Hg(0)
  • Molecular, environmental, occupational, and accidental toxicity of Hg(II)
  • Molecular, environmental, occupational, and accidental toxicity of (CH3Hg(II)) or ethylmercury (CH3CH2Hg(II))
  • Development of strategies to reduce mercury toxicity

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jbb/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 831890
  • - Editorial

Mercury Toxicity

João B. T. Rocha | Michael Aschner | ... | Luiz Carlos L. Silveira
  • Special Issue
  • - Volume 2012
  • - Article ID 924549
  • - Review Article

Mercury Toxicity on Sodium Pump and Organoseleniums Intervention: A Paradox

Ige Joseph Kade
  • Special Issue
  • - Volume 2012
  • - Article ID 248764
  • - Review Article

Role of Calcium and Mitochondria in MeHg-Mediated Cytotoxicity

Daniel Roos | Rodrigo Seeger | ... | Nilda Vargas Barbosa
  • Special Issue
  • - Volume 2012
  • - Article ID 256965
  • - Research Article

Mercury Disposition in Suckling Rats: Comparative Assessment Following Parenteral Exposure to Thiomersal and Mercuric Chloride

Maja Blanuša | Tatjana Orct | ... | Martina Piasek
  • Special Issue
  • - Volume 2012
  • - Article ID 681016
  • - Research Article

Dietary Mercury Exposure Resulted in Behavioral Differences in Mice Contaminated with Fish-Associated Methylmercury Compared to Methylmercury Chloride Added to Diet

Jean-Paul Bourdineaud | Masumi Marumoto | ... | Masatake Fujimura
  • Special Issue
  • - Volume 2012
  • - Article ID 635075
  • - Research Article

Methyl Mercury Exposure at Niigata, Japan: Results of Neurological Examinations of 103 Adults

Kimio Maruyama | Takashi Yorifuji | ... | Hisashi Saito
  • Special Issue
  • - Volume 2012
  • - Article ID 589569
  • - Review Article

Oral Lichenoid Contact Lesions to Mercury and Dental Amalgam—A Review

Helen McParland | Saman Warnakulasuriya
  • Special Issue
  • - Volume 2012
  • - Article ID 359879
  • - Research Article

Biomarkers of Adverse Response to Mercury: Histopathology versus Thioredoxin Reductase Activity

Vasco Branco | Paula Ramos | ... | Cristina Carvalho
  • Special Issue
  • - Volume 2012
  • - Article ID 254582
  • - Research Article

Exposure to Low Dose of Cinnabar (a Naturally Occurring Mercuric Sulfide (HgS)) Caused Neurotoxicological Effects in Offspring Mice

Chun-Fa Huang | Chuan-Jen Hsu | ... | Shoei-Yn Lin-Shiau
  • Special Issue
  • - Volume 2012
  • - Article ID 472858
  • - Research Article

Five Hundred Years of Mercury Exposure and Adaptation

Guido Lombardi | Antonio Lanzirotti | ... | Otto Appenzeller
BioMed Research International
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Acceptance rate8%
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