Minimally invasive dental procedures are the new paradigm in healthcare. Scientific progress and developments have led to modifications of older concepts. Modern dentistry has placed an emphasis on minimally invasive and personalized treatments in recent years. Minimal intervention dentistry focuses on the control of the disease, remineralizing early lesions, and performing minimal intervention surgical procedures. In addition, minimally invasive dentistry emphasizes the philosophy of prevention, remineralization, minimally invasive restorative treatments, and using less invasive surgical approach treatments. Digital dentistry has been also aided the minimal intervention treatments. This includes the use of natural substances to reduce the incidence of acute and chronic inflammation, such as probiotics, paraprobiotics, postbiotics, ozone therapy, laser therapy, the use of micro-abrasive powders, and minimally invasive instruments for the clinical management of dental and periodontal tissues.

Furthermore, an extension of minimal intervention is minimizing treatment failures, and providing natural aids by gradually decreasing the chemical pharmacological actions, and focusing on proactive intervention. Despite the advantages of minimally invasive dental treatment procedures, recognition in the scientific community and the practical application of these minimally invasive procedures is not yet widespread in oral health programs. For these implementations, instruments and procedures have limitations to be addressed. An important consideration is the adequate knowledge and training of the clinical practitioners for use of these instruments and procedures. Moreover, the cost of the equipment and materials is a deciding factor for clinical practitioners. The future of minimally invasive dentistry lies in the development of remineralizing agents that have the capability to remineralize caries lesions as well as smart biomimetic materials to restore and replace the tooth structure.

This Special Issue invites clinicians and researchers to submit high-quality original research and review articles focused on minimally invasive treatments in clinical dentistry.

Potential topics include but are not limited to the following:

• Preventive oral health treatments such as enamel remineralization, dentinal treatments, and fluoride therapy
• Dental caries management using minimally invasive restorations such as atraumatic restorative treatment strategies
• Advances in various restorative dental materials for preventive purposes
• Non-surgical therapy and tissue regeneration in peri-implant mucositis and peri-implantitis
• Minimally invasive surgical reconstruction procedures such as the use of lasers in clinical dentistry
• Minimally invasive prosthetic restorative treatments using digital technologies