Enzymes are considered as potential biocatalysts for a large number of reactions. Particularly, the microbial enzymes have widespread uses in industries and medicine. The microbial enzymes are also more active and stable than plant and animal enzymes. In addition, the microorganisms represent an alternative source of enzymes because they can be cultured in large quantities in a short time by fermentation and owing to their biochemical diversity and their susceptibility to gene manipulation. Recently, many novel enzymes isolated mainly from extremophiles and are likely to mimic some of the unnatural product of the enzymes that are desirable for further commercial applications. In demand of the enzymes, industries are looking for new microbial strains to produce the enzymes to fulfill the requirements.

Mainly this special issue focuses on the production and application oriented in industry and medical field. We invite the researchers to contribute with original articles as well as reviews. Potential topics include, but are not limited to:

• Microbial enzymes from extremophiles
• Microbial enzymes applications in industries
• Microbial enzymes applications in medicine
• Improve the enzyme production by fermentation technique and molecular approach
• Biodegradation and bioremediation

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/biotechnology/me/ according to the following timetable: