BioMed Research International

The Epithelium–Molecular Landscaping for an Interactive Barrier


Publishing date
01 Jan 2010
Status
Published
Submission deadline
01 Jul 2009

Lead Editor

1Department of Molecular Biology and Microbiology, School of Medicine, University of Central Florida College of Medicine, Orlando, FL 32816, USA

2Department of Nephrology, Kumamoto University Graduate School of Medical Sciences, Kumamoto 860-8556, Japan

3UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland

4Departments of Urology and Pathology, NYU Langone Medical Center, New York, NY 10016, USA


The Epithelium–Molecular Landscaping for an Interactive Barrier

Description

The epithelium is the most unique structure of the body as it is the layer that faces the outside environment. The epithelium must protect the body from the various environmental insults, such as pathogens, particles, and mechanical forces. In this role, the epithelium will sustain injuries, which must then be properly repaired to restore the original tissue structure and integrity. The epithelium must at the same time allow material transfer and exchange with the outside environment, absorbing nutrients, and removing waste. At the plasma membrane of the epithelial cells, these tasks are carried out by structural proteins and protein complexes, receptors, channels, carriers and pumps, and proteases. These molecules must be delivered to the appropriate topological location, while the abundance and activities of these molecules must also be precisely regulated. The goal of this special issue is to develop a comprehensive picture of the epithelial membrane molecular landscape in multiple dimensions: transport and trafficking, changes during normal tissue development and differentiation, changes during tissue injury, and changes during tissue repair and regeneration.

We are inviting original research and review articles addressing the epithelial membrane molecular landscape with a functional interpretation on the dynamic roles played by the epithelium. The topics to be considered include, but are not limited to:

  • Intercellular adhesions and junctions
  • Channels, carriers, and pumps
  • Membrane-anchored receptors
  • Membrane-anchored proteases
  • Endocytosis, recycling of membrane proteins, and transcytosis
  • Invasion of pathogens
  • Mechanosensing
  • Epithelial-matrix adhesions

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jbb/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2010
  • - Article ID 793843
  • - Research Article

Regulation of Adrenal Aldosterone Production by Serine Protease Prostasin

Takehiro Ko | Yutaka Kakizoe | ... | Kenichiro Kitamura
  • Special Issue
  • - Volume 2010
  • - Article ID 278948
  • - Review Article

Tight Junctions in Salivary Epithelium

Olga J. Baker
  • Special Issue
  • - Volume 2010
  • - Article ID 190724
  • - Review Article

The Retinal Pigment Epithelium: Something More than a Constituent of the Blood-Retinal Barrier—Implications for the Pathogenesis of Diabetic Retinopathy

Rafael Simó | Marta Villarroel | ... | Marta Garcia-Ramírez
  • Special Issue
  • - Volume 2010
  • - Article ID 974943
  • - Review Article

Interaction of Botulinum Toxin with the Epithelial Barrier

Yukako Fujinaga
  • Special Issue
  • - Volume 2010
  • - Article ID 305879
  • - Review Article

Molecular Modulation of Intestinal Epithelial Barrier: Contribution of Microbiota

Renu Sharma | Christopher Young | Josef Neu
  • Special Issue
  • - Volume 2010
  • - Article ID 850320
  • - Research Article

Receptor-Mediated and Fluid-Phase Transcytosis of Horseradish Peroxidase across Rat Hepatocytes

Isabella Ellinger | Renate Fuchs
  • Special Issue
  • - Volume 2010
  • - Article ID 917108
  • - Review Article

The Receptor for Advanced Glycation End Products (RAGE) and the Lung

Stephen T. Buckley | Carsten Ehrhardt
  • Special Issue
  • - Volume 2010
  • - Article ID 264704
  • - Research Article

Aquaporin-6 Expression in the Cochlear Sensory Epithelium Is Downregulated by Salicylates

Paola Perin | Simona Tritto | ... | Umberto Laforenza
  • Special Issue
  • - Volume 2010
  • - Article ID 525034
  • - Research Article

The Vacuolar-Type -ATPase in Ovine Rumen Epithelium is Regulated by Metabolic Signals

Judith Kuzinski | Rudolf Zitnan | ... | Monika Schweigel
  • Special Issue
  • - Volume 2010
  • - Article ID 696034
  • - Research Article

Phenotypic Transition of the Collecting Duct Epithelium in Congenital Urinary Tract Obstruction

Peter Trnka | Michael J. Hiatt | ... | Douglas G. Matsell
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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