BioMed Research International

Integrated Analysis of Multiscale Large-Scale Biological Data for Investigating Human Disease 2016


Publishing date
02 Sep 2016
Status
Published
Submission deadline
15 Apr 2016

Lead Editor

1Chinese Academy of Sciences, Shanghai, China

2Shanghai Maritime University, Shanghai, China

3Monash University, Clayton, Australia

4Icahn School of Medicine at Mount Sinai, New York, USA

5University of Rochester, Rochester, USA


Integrated Analysis of Multiscale Large-Scale Biological Data for Investigating Human Disease 2016

Description

Integrating large-scale data obtained from multiscales is essential for understanding the molecular basis of complex diseases and providing useful therapeutic targets. Several large projects, such as The Cancer Genome Atlas (TCGA), Cancer Cell Line Encyclopedia (CCLE), Genotype-Tissue Expression (GTEx), and Molecular Taxonomy of Breast Cancer International Consortium (METABRIC), have measured the somatic mutation, copy number variation (CNV), mRNA expression, microRNA expression, and methylation data and made them publicly available. Recently, many statistical methods and analysis tools have been developed based on these multiscale large-scale data.

A special issue of research as well as review articles in these research fields is important and timely. The potential contributors for the special issue are oncologist, computational biologists, mathematical biologists, bioinformaticians, systems biologists, and computational pharmacist. We invite authors to contribute original research articles as well as review articles to this special issue.

Potential topics include, but are not limited to:

  • Subtype stratification of patients
  • Multiscale network construction
  • Network module identification
  • Predictive model of disease state
  • Biomarker discovery
  • Combinatorial drug discovery
  • Translational medicine
  • Novel computational methods in large biology data analysis
  • Inferring gene function from expression data
  • Inferring gene function from genome sequence data
  • Integrating expression data with other genome-wide data for functional annotation
  • Integrating expression data from different organisms

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 6585069
  • - Editorial

Integrated Analysis of Multiscale Large-Scale Biological Data for Investigating Human Disease 2016

Tao Huang | Lei Chen | ... | Zhenguo Zhang
  • Special Issue
  • - Volume 2016
  • - Article ID 8072463
  • - Review Article

New Trends of Digital Data Storage in DNA

Pavani Yashodha De Silva | Gamage Upeksha Ganegoda
  • Special Issue
  • - Volume 2016
  • - Article ID 5469371
  • - Research Article

Analyzing the miRNA-Gene Networks to Mine the Important miRNAs under Skin of Human and Mouse

Jianghong Wu | Husile Gong | ... | Wenguang Zhang
  • Special Issue
  • - Volume 2016
  • - Article ID 4241293
  • - Review Article

Differential Regulatory Analysis Based on Coexpression Network in Cancer Research

Junyi Li | Yi-Xue Li | Yuan-Yuan Li
  • Special Issue
  • - Volume 2016
  • - Article ID 9721713
  • - Research Article

Hybrid Binary Imperialist Competition Algorithm and Tabu Search Approach for Feature Selection Using Gene Expression Data

Shuaiqun Wang | Aorigele | ... | Xiaomin Hong
  • Special Issue
  • - Volume 2016
  • - Article ID 3952494
  • - Research Article

Predicting Diagnostic Gene Biomarkers for Non-Small-Cell Lung Cancer

Bin Liang | Yang Shao | ... | Shu-Juan Jiang
  • Special Issue
  • - Volume 2016
  • - Article ID 6945304
  • - Research Article

A Five-Gene Expression Signature Predicts Clinical Outcome of Ovarian Serous Cystadenocarcinoma

Li-Wei Liu | Qiuhao Zhang | ... | Qiang Wang
  • Special Issue
  • - Volume 2016
  • - Article ID 2714341
  • - Research Article

DASAF: An R Package for Deep Sequencing-Based Detection of Fetal Autosomal Abnormalities from Maternal Cell-Free DNA

Baohong Liu | Xiaoyan Tang | ... | Guohui Ding
  • Special Issue
  • - Volume 2016
  • - Article ID 4895476
  • - Research Article

The Use of Protein-Protein Interactions for the Analysis of the Associations between PM2.5 and Some Diseases

Qing Zhang | Pei-Wei Zhang | Yu-Dong Cai
  • Special Issue
  • - Volume 2016
  • - Article ID 5237827
  • - Research Article

The Occurrence of Genetic Alterations during the Progression of Breast Carcinoma

Xiao-Chen Li | Chenglin Liu | ... | Yang Zhong
BioMed Research International
 Journal metrics
Acceptance rate30%
Submission to final decision67 days
Acceptance to publication31 days
CiteScore3.600
Impact Factor2.276
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