BioMed Research International

Plasminogen Receptors


Publishing date
24 Aug 2012
Status
Published
Submission deadline
24 Feb 2012

1Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA

2Department of Medicine, University of California, San Diego and Veterans Administration San Diego Healthcare System, San Diego, CA 92093, USA

3Department of Molecular Cardiology, Cleveland Clinic, Cleveland, OH 44195, USA

4Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, NS, Canada B3H 4R2


Plasminogen Receptors

Description

Plasminogen receptors are very broadly distributed on both prokaryotic and eukaryotic cells. Plasminogen receptors function to promote the activation of the circulating zymogen, plasminogen, to the broad-spectrum protease, plasmin. In addition to fibrinolysis, cell-bound plasmin has the capacity to process proteins of the extracellular matrix to enable physiological and pathophysiological processes requiring cell migration (including inflammation, tissue remodeling, wound healing, tumor cell invasion and metastasis, skeletal myogenesis, and neurite outgrowth) as well as to process prohormones. Recent developments with knockout mice, transfection studies, specific knockdown, and specific antibody blockade have identified new functions for plasminogen receptors.

We are interested in articles that identify physiologic and pathologic roles of specific plasminogen receptors. Potential topics include, but are not limited to:

  • The role of plasminogen receptors in physiological and pathophysiological processes
  • Mechanisms of regulation of expression of plasminogen receptors
  • The interplay between plasminogen receptors and plasminogen activator receptors
  • Plasminogen receptors as a component of the proteolytic hub
  • The role of plasminogen receptors in plasmin-dependent regulation of other proteases
  • Knockout mouse models of plasminogen receptors
  • Structure-function studies
  • Bacterial plasminogen receptors

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jbb/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 130735
  • - Editorial

Plasminogen Receptors

Lindsey A. Miles | Edward F. Plow | ... | Robert J. Parmer
  • Special Issue
  • - Volume 2012
  • - Article ID 136302
  • - Review Article

Potential Role of Kringle-Integrin Interaction in Plasmin and uPA Actions (A Hypothesis)

Yoshikazu Takada
  • Special Issue
  • - Volume 2012
  • - Article ID 758513
  • - Review Article

Plasminogen Binding Proteins and Plasmin Generation on the Surface of Leptospira spp.: The Contribution to the Bacteria-Host Interactions

Monica L. Vieira | Marina V. Atzingen | ... | Ana L. T. O. Nascimento
  • Special Issue
  • - Volume 2012
  • - Article ID 417675
  • - Review Article

The Role of Nephritis-Associated Plasmin Receptor (NAPlr) in Glomerulonephritis Associated with Streptococcal Infection

Takashi Oda | Nobuyuki Yoshizawa | ... | Hiroo Kumagai
  • Special Issue
  • - Volume 2012
  • - Article ID 272148
  • - Review Article

Bacterial Plasminogen Receptors: Mediators of a Multifaceted Relationship

Martina L. Sanderson-Smith | David M. P. De Oliveira | ... | Jason D. McArthur
  • Special Issue
  • - Volume 2012
  • - Article ID 437920
  • - Review Article

The Plasminogen System in Regulating Stem Cell Mobilization

Yanqing Gong | Jane Hoover-Plow
  • Special Issue
  • - Volume 2012
  • - Article ID 406273
  • - Review Article

The Annexin A2/S100A10 System in Health and Disease: Emerging Paradigms

Nadia Hedhli | Domenick J. Falcone | ... | Katherine A. Hajjar
  • Special Issue
  • - Volume 2012
  • - Article ID 564259
  • - Review Article

Cell Surface Remodeling by Plasmin: A New Function for an Old Enzyme

Elena I. Deryugina | James P. Quigley
  • Special Issue
  • - Volume 2012
  • - Article ID 208108
  • - Review Article

Accelerated Fibrinolysis and Its Propagation on Vascular Endothelial Cells by Secreted and Retained tPA

Tetsumei Urano | Yuko Suzuki
  • Special Issue
  • - Volume 2012
  • - Article ID 156795
  • - Review Article

α-Enolase, a Multifunctional Protein: Its Role on Pathophysiological Situations

Àngels Díaz-Ramos | Anna Roig-Borrellas | ... | Roser López-Alemany
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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