BioMed Research International

Neurodegeneration: Etiologies and New Therapies


Publishing date
26 Sep 2014
Status
Published
Submission deadline
09 May 2014

Lead Editor

1Department of Neurology, Singapore General Hospital, National Neuroscience Institute and Duke NUS Graduate Medical School, Singapore

2Russell H. Morgan Department of Radiology and Radiological Science and Institute for Cell Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA

3Department of Neurology, Division of Neuromuscular Medicine, and Department of Physical Medicine and Rehabilitation, The Ohio State University, Columbus, OH 43210, USA

4Toxicogenomics and Predictive Toxicology Division, CSIR-Indian Institute of Toxicology Research, Lucknow, Uttar Pradesh 226 001, India

5Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA


Neurodegeneration: Etiologies and New Therapies

Description

Neurodegeneration is seen in many nervous system disorders such as Alzheimer’s disease, amyotrophic lateral sclerosis, Parkinson’s disease, multiple sclerosis, cerebral stroke, Huntington’s disease, and several other neurological conditions. These diseases have devastating effects on patients and are often accompanied by tremendous physical and emotional burden not only for the patients but also for their families and friends as well. These disorders are not only amongst the most costly diseases to society but also their increasing prevalence poses a serious public health problem. Just three decades ago very little was known about the causes of neurodegeneration. However, several breakthroughs in recent years have provided some notable insights. Although substantial progress has been made, more detailed studies are needed to understand the cause and molecular mechanisms of neurodegeneration in order to identify potential targets and to provide corrective interventions in addition to supportive treatments.

In this special issue, we invite investigators to contribute original research articles and reviews exploring molecular mechanism of neurodegeneration, new diagnostic tools, and innovative approaches for treatment. Potential topics include, but are not limited to:

  • New in vivo and in vitro models to study neurodegeneration
  • Development and validation of biomarkers to improve the diagnosis
  • New risk factors for neurodegenerative diseases
  • Neurochemistry and/or molecular mechanisms of neurodegeneration
  • New therapeutic targets for treatment
  • Stem cell and gene-based therapies in neurodegenerative disorders

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/neuroscience/ndde/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 291531
  • - Research Article

Transgenic Rat Model of Huntington’s Disease: A Histopathological Study and Correlations with Neurodegenerative Process in the Brain of HD Patients

Yvona Mazurová | Miroslava Anderova | ... | Aleš Bezrouk
  • Special Issue
  • - Volume 2014
  • - Article ID 401306
  • - Review Article

The Emerging Use of In Vivo Optical Imaging in the Study of Neurodegenerative Diseases

Aileen P. Patterson | Stephanie A. Booth | Reuben Saba
  • Special Issue
  • - Volume 2014
  • - Article ID 298020
  • - Review Article

Apocynin, a Low Molecular Oral Treatment for Neurodegenerative Disease

Bert A. ‘t Hart | Sjef Copray | Ingrid Philippens
  • Special Issue
  • - Volume 2014
  • - Article ID 837157
  • - Review Article

Potential Therapeutic Strategies for Alzheimer’s Disease Targeting or Beyond β-Amyloid: Insights from Clinical Trials

Qiutian Jia | Yulin Deng | Hong Qing
  • Special Issue
  • - Volume 2014
  • - Article ID 292471
  • - Research Article

Reduction of Experimental Cerebral Malaria and Its Related Proinflammatory Responses by the Novel Liposome-Based β-Methasone Nanodrug

Jintao Guo | Judith H. Waknine-Grinberg | ... | Jacob Golenser
  • Special Issue
  • - Volume 2014
  • - Article ID 281510
  • - Clinical Study

Improvement of Oxidative and Metabolic Parameters by Cellfood Administration in Patients Affected by Neurodegenerative Diseases on Chelation Treatment

Alessandro Fulgenzi | Rachele De Giuseppe | ... | Maria Elena Ferrero
  • Special Issue
  • - Volume 2014
  • - Article ID 728038
  • - Review Article

Gambling Disorder during Dopamine Replacement Treatment in Parkinson’s Disease: A Comprehensive Review

Domenico Pirritano | Massimiliano Plastino | ... | Giovambattista De Sarro
  • Special Issue
  • - Volume 2014
  • - Article ID 568587
  • - Research Article

Improvements in Memory after Medial Septum Stimulation Are Associated with Changes in Hippocampal Cholinergic Activity and Neurogenesis

Da Un Jeong | Ji Eun Lee | ... | Jin Woo Chang
  • Special Issue
  • - Volume 2014
  • - Article ID 936891
  • - Review Article

ATP Release through Lysosomal Exocytosis from Peripheral Nerves: The Effect of Lysosomal Exocytosis on Peripheral Nerve Degeneration and Regeneration after Nerve Injury

Junyang Jung | Hyun Woo Jo | ... | Na Young Jeong
  • Special Issue
  • - Volume 2014
  • - Article ID 297241
  • - Review Article

Therapeutically Targeting Neuroinflammation and Microglia after Acute Ischemic Stroke

Youngjeon Lee | Sang-Rae Lee | ... | Hong J. Lee
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