BioMed Research International

Pharmacological Application of Growth Factors: Basic and Clinical


Publishing date
25 Jul 2014
Status
Published
Submission deadline
07 Mar 2014

Lead Editor

1School of Pharmacy, Wenzhou Medical University, Chashan University-Town, Wenzhou 325035, China

2Department of Bioengineering, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA

3Excellence Cluster Cardio Pulmonary System, University Justus Liebig Giessen, Aulweg 130, 35392 Giessen, Germany


Pharmacological Application of Growth Factors: Basic and Clinical

Description

Growth factors are proteins that function as growth stimulators, increase cell survival, and activate migration, proliferation, and differentiation. Several growth factors such as fibroblast growth factor (FGF), epidermal growth factor (EGF), and nerve growth factor (NGF) play a key role in brain or spinal cord injury and acute organ injuries. Vascular endothelial growth factor (VEGF) increases vascular permeability and induces angiogenesis and vasculogenesis, which is applied in the treatment of ischemic heart disease and so on. One of the main functions of growth factors is to promote cell proliferation which is essential for wound healing, tissue repair, and regeneration. Latest studies also figured out another effect on metabolism. However, the molecular mechanisms of growth factors treatment are still undefined. Thus, further investigations on mechanisms of growth factors in basic and clinical research are urgent.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the molecular mechanisms of growth factors in the studies on basic or clinical research such as neuronal diseases, acute injury, wound healing, tissue engineering and organ repair, and vasculogenesis to improve the development of growth factors as new drugs in the therapeutic strategies. Potential topics include, but are not limited to:

  • Pharmacological application of growth factors in neuronal diseases
  • Recent developments and mechanisms of growth factors in basic or clinical studies on wound healing
  • Development of growth factors in organ injury and repair
  • Recent advances of growth factors in basic or clinical research of vasculogenesis
  • Pharmacological application of growth factors in tissue engineering

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/pharmacology/pagf/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 141794
  • - Editorial

Pharmacological Application of Growth Factors: Basic and Clinical

Jian Xiao | Yadong Wang | ... | Xiaokun Li
  • Special Issue
  • - Volume 2015
  • - Article ID 730139
  • - Research Article

Fibroblast Growth Factors Stimulate Hair Growth through β-Catenin and Shh Expression in C57BL/6 Mice

Wei-hong Lin | Li-Jun Xiang | ... | Jian Xiao
  • Special Issue
  • - Volume 2014
  • - Article ID 154702
  • - Review Article

Targeting Mast Cells Tryptase in Tumor Microenvironment: A Potential Antiangiogenetic Strategy

Michele Ammendola | Christian Leporini | ... | Girolamo Ranieri
  • Special Issue
  • - Volume 2014
  • - Article ID 759473
  • - Review Article

The Nerve Growth Factor Signaling and Its Potential as Therapeutic Target for Glaucoma

Haitao Wang | Rikang Wang | ... | Wenhua Zheng
  • Special Issue
  • - Volume 2014
  • - Article ID 547187
  • - Research Article

NGF Accelerates Cutaneous Wound Healing by Promoting the Migration of Dermal Fibroblasts via the PI3K/Akt-Rac1-JNK and ERK Pathways

Ji-Cai Chen | Bei-Bei Lin | ... | Rui-Jie Chen
  • Special Issue
  • - Volume 2014
  • - Article ID 697935
  • - Review Article

Neuropathologic Implication of Peripheral Neuregulin-1 and EGF Signals in Dopaminergic Dysfunction and Behavioral Deficits Relevant to Schizophrenia: Their Target Cells and Time Window

Hiroyuki Nawa | Hidekazu Sotoyama | ... | Hisaaki Namba
  • Special Issue
  • - Volume 2014
  • - Article ID 807874
  • - Research Article

ATF4- and CHOP-Dependent Induction of FGF21 through Endoplasmic Reticulum Stress

Xiao-shan Wan | Xiang-hong Lu | ... | Xiao-kun Li
  • Special Issue
  • - Volume 2014
  • - Article ID 261672
  • - Review Article

Association between Risk Factors for Vascular Dementia and Adiponectin

Juhyun Song | Won Taek Lee | ... | Jong Eun Lee
  • Special Issue
  • - Volume 2014
  • - Article ID 601084
  • - Review Article

Potential Therapeutic Effects of Neurotrophins for Acute and Chronic Neurological Diseases

Junying Cai | Fuzhou Hua | ... | Yanhui Hu
  • Special Issue
  • - Volume 2014
  • - Article ID 579632
  • - Research Article

Recombinant Keratinocyte Growth Factor 1 in Tobacco Potentially Promotes Wound Healing in Diabetic Rats

Zhi-Guo Feng | Shi-Feng Pang | ... | Yi Lin
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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