BioMed Research International

Diseases of Pregnancy and Fetal Programming: Cell and Molecular Mechanisms


Publishing date
01 Aug 2014
Status
Published
Submission deadline
14 Mar 2014

Lead Editor

1Faculty of Medicine, Pontificia Universidad Católica de Chile, Marcoleta 391, Santiago, Chile

2Center for Pregnancy and Newborn Research, University of Texas Health Science Center, San Antonio, TX, USA

3The University of Queensland Center for Clinical Research, Herston, Brisbane, QLD, Australia


Diseases of Pregnancy and Fetal Programming: Cell and Molecular Mechanisms

Description

A well-documented and accepted explanation of the origins of diseases that occur with a high frequency in adulthood is the relationship between an adverse intrauterine environment during fetal life and development of diseases including hypertension, diabetes, obesity, insulin resistance, and metabolic syndrome. Several epidemiological studies have served as the basis for investigating actual studies determining cell and molecular mechanisms behind these alterations. However, these mechanisms are at present partially described. It is expected that continuation of these studies will yield further evidence regarding potential aspects such as timing in pregnancy and consequences of these alterations in the intrauterine life on the appearance and management of adulthood diseases. In addition, few studies have addressed concerning whether the preconceptional period is also involved in this phenomenon.

We invite investigators to contribute original research articles as well as review articles that will stimulate ongoing efforts for a better understanding of the cell and molecular mechanisms underlying fetal programming of adult diseases. We will be looking for contributions over a wide area of expertise but particularly those studying the vascular physiology/pathophysiology of diseases of pregnancy that could result in programming of the fetus. The areas of systemic physiology, cell physiology, molecular physiology, epigenetics, proteomics, and metabolomics are welcomed. Specific studies using animal models and cell lines are acceptable. Potential topics include, but are not limited to:

  • Placenta angiogenesis and vasculogenesis
  • Placental vascular dysfunction
  • Placental microvascular and macrovascular endothelial dysfunction
  • Preconception care of pregnancy and programming of adult diseases
  • Fetal evidence for programming of adult diseases (early evidence)
  • Newborn evidence for programming of adult diseases (early evidence)
  • Epigenetics and placenta programming
  • Proteomics and metabolomics as tools in programming
  • Lipid signalling in the placenta
  • Insulin signalling in the placenta
  • Nucleoside and nucleotide signalling in the placenta
  • Obesity in pregnancy
  • Oxidative stress in pregnancy
  • Gestational diabetes mellitus
  • Preeclampsia
  • Intrauterine growth restriction
  • Premature rupture of membranes (PROM)
  • Fetal hypoxia

Before submission authors should carefully read over the journal’s Author Guidelines which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/physiology/preg/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 937050
  • - Editorial

Diseases of Pregnancy and Fetal Programming: Cell and Molecular Mechanisms

Luis Sobrevia | Leslie Myatt | Gregory Rice
  • Special Issue
  • - Volume 2014
  • - Article ID 693157
  • - Review Article

The Possible Role of Extravillous Trophoblast-Derived Exosomes on the Uterine Spiral Arterial Remodeling under Both Normal and Pathological Conditions

Carlos Salomon | Sarah W. Yee | ... | Gregory E. Rice
  • Special Issue
  • - Volume 2014
  • - Article ID 280497
  • - Research Article

Early Onset Intrauterine Growth Restriction in a Mouse Model of Gestational Hypercholesterolemia and Atherosclerosis

Dolores Busso | Lilian Mascareño | ... | Attilio Rigotti
  • Special Issue
  • - Volume 2014
  • - Article ID 676758
  • - Review Article

DNA Damage and Its Cellular Response in Mother and Fetus Exposed to Hyperglycemic Environment

Jusciele Brogin Moreli | Janine Hertzog Santos | ... | Iracema Mattos Paranhos Calderon
  • Special Issue
  • - Volume 2014
  • - Article ID 597357
  • - Research Article

Effect of Hypoxia on the Calcium and Magnesium Content, Lipid Peroxidation Level, and Ca2+-ATPase Activity of Syncytiotrophoblast Plasma Membranes from Placental Explants

Delia I. Chiarello | Reinaldo Marín | ... | Cilia Abad
  • Special Issue
  • - Volume 2014
  • - Article ID 949361
  • - Research Article

Perinatal Nitric Oxide Therapy Prevents Adverse Effects of Perinatal Hypoxia on the Adult Pulmonary Circulation

Anne-Christine Peyter | Flavien Delhaes | ... | Jean-François Tolsa
  • Special Issue
  • - Volume 2014
  • - Article ID 353616
  • - Review Article

Role of Lectin-Like Oxidized Low Density Lipoprotein-1 in Fetoplacental Vascular Dysfunction in Preeclampsia

Felipe A. Zuniga | Valeska Ormazabal | ... | Claudio Aguayo
  • Special Issue
  • - Volume 2014
  • - Article ID 917672
  • - Review Article

Programming of Fetal Insulin Resistance in Pregnancies with Maternal Obesity by ER Stress and Inflammation

Francisco Westermeier | Pablo J. Sáez | ... | Marcelo Farías-Jofré
  • Special Issue
  • - Volume 2014
  • - Article ID 472017
  • - Research Article

Associations of Prenatal Growth with Metabolic Syndrome, Insulin Resistance, and Nutritional Status in Chilean Children

Francisco Mardones | Pilar Arnaiz | ... | Oscar Castillo
  • Special Issue
  • - Volume 2014
  • - Article ID 526895
  • - Review Article

Docosahexaenoic Acid Supplementation Early in Pregnancy May Prevent Deep Placentation Disorders

Jorge A. Carvajal
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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