BioMed Research International

Animal Models of Human Pathology 2013


Publishing date
29 Nov 2013
Status
Published
Submission deadline
12 Jul 2013

Lead Editor

1Institute of Experimental Endocrinology and Oncology, National Research Council, Naples, Italy

2NeuroEndocrine Interactions in Rheumatology and Inflammatory Diseases, Santiago University Clinical Hospital, Santiago de Compostela, Spain

3Department of Molecular Virology, Immunology & Medical Genetics, The Ohio State University, Columbus, OH, USA


Animal Models of Human Pathology 2013

Description

Based on the genetic alterations found in humans, multiple models of human pathologies have been generated in genetically engineered or drug-induced animals. These experimental models are valuable tools for understanding physiopathology of the disease and discovering novel therapeutic targets and drugs. In fact, one avenue holding tremendous potential to find therapies against human diseases is the use of intact living systems, where complex biological processes can be examined.

We invite authors to present original research articles as well as review articles that will stimulate the continuing efforts in developing animal models, ranging from invertebrates to large animals, to be used in preclinical applications, improving therapy in various fields of medicine (oncology, cardiovascular, immunology, endocrinology, brain pathologies, etc.). We are particularly interested in manuscripts that report naturally occurring, induced, or engineered animal models of human diseases and their preclinical applications. Reviews that summarize all the animal models for a particular pathology, their involvement in preclinical trials, and their future in treatment practice are also particularly welcome. Potential topics include, but are not limited to:

  • Modeling retinoblastoma in rodents
  • The use of animal models in the study of obesity
  • The value of animal models for drug development in autoimmune diseases
  • The genetics of cardiovascular disease: new insights from animal models
  • Understanding pathogenesis and therapy of ataxia telangiectasia (AT) via animal models
  • Experimental animal models of rheumatoid arthritis, lupus erythematosus, and osteoarthritis
  • Small model organisms for neurodegenerative diseases
  • Large animal models of heart failure
  • The pig: a representative animal model for humans
  • Modeling human disease using the nematode Caenorhabditis elegans
  • Drosophila models of human diseases

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/pathology/amhp13/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 861424
  • - Editorial

Animal Models of Human Pathology 2013

Monica Fedele | Oreste Gualillo | Andrea Vecchione
  • Special Issue
  • - Volume 2014
  • - Article ID 240642
  • - Review Article

Animal Models in Studies of Cardiotoxicity Side Effects from Antiblastic Drugs in Patients and Occupational Exposed Workers

Monica Lamberti | Giancarlo Giovane | ... | Marina Di Domenico
  • Special Issue
  • - Volume 2014
  • - Article ID 130894
  • - Review Article

A Role for T-Lymphocytes in Human Breast Cancer and in Canine Mammary Tumors

Maria Isabel Carvalho | Isabel Pires | ... | Felisbina L. Queiroga
  • Special Issue
  • - Volume 2014
  • - Article ID 234295
  • - Review Article

Glix 13, a New Drug Acting on Glutamatergic Pathways in Children and Animal Models of Autism Spectrum Disorders

Annamaria Chiara Santini | Giovanna Maria Pierantoni | ... | Carla Sogos
  • Special Issue
  • - Volume 2013
  • - Article ID 617569
  • - Research Article

Obesity, Insulin Resistance, and Metabolic Syndrome: A Study in WNIN/Ob Rats from a Pancreatic Perspective

Vijayalakshmi Venkatesan | Soundarya L. Madhira | ... | Giridharan Nappanveettil
  • Special Issue
  • - Volume 2013
  • - Article ID 938047
  • - Research Article

A Nonthoracotomy Myocardial Infarction Model in an Ovine Using Autologous Platelets

Tyler Spata | Daniel Bobek | ... | Ahmet Kilic
  • Special Issue
  • - Volume 2013
  • - Article ID 810423
  • - Research Article

Curcumin Inhibits Tumor Growth and Angiogenesis in an Orthotopic Mouse Model of Human Pancreatic Cancer

Sabrina Bimonte | Antonio Barbieri | ... | Claudio Arra
  • Special Issue
  • - Volume 2013
  • - Article ID 392434
  • - Research Article

17β-Estradiol Attenuates Poststroke Depression and Increases Neurogenesis in Female Ovariectomized Rats

Yifan Cheng | Qiaoer Su | ... | Kunlin Jin
  • Special Issue
  • - Volume 2013
  • - Article ID 180453
  • - Research Article

A Posteriori Comparison of Natural and Surgical Destabilization Models of Canine Osteoarthritis

Maxim Moreau | Jean-Pierre Pelletier | ... | Eric Troncy
  • Special Issue
  • - Volume 2013
  • - Article ID 208912
  • - Research Article

Modification of a Rodent Hindlimb Model of Secondary Lymphedema: Surgical Radicality versus Radiotherapeutic Ablation

Hyung Sub Park | In Mok Jung | ... | Taeseung Lee
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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