BioMed Research International

Biomarker and Translational Prostate Cancer Research


Status
Published

Lead Editor

1Research Unit in Biomedicine and Translational Oncology, Vall d’Hebron Research Institute, 08035 Barcelona, Spain

2Cancer Genetics, University of East Anglia, Norwich Norfolk NR4 7TJ, UK

3Australian Prostate Cancer Research Centre, Brisbane, QLD 4102 Australia


Biomarker and Translational Prostate Cancer Research

Description

The existing clinical biomarkers for prostate cancer (PCa) are not ideal, since they cannot specifically differentiate between those patients who should be treated immediately and those who should avoid overtreatment. Current screening techniques lack specificity, and a decisive diagnosis of PCa is based on prostate biopsy. Although PCa screening is widely utilized nowadays, two-thirds of the biopsies performed are still unnecessary. Thus, the discovery of noninvasive PCa biomarkers remains an urgent unmet medical need. Once metastasized, there is still no curative therapy. A better understanding of sustained androgen receptor signaling in castration resistant prostate cancer (CRPC) has now led to the development of more effective therapies. We need a better understanding of the molecular and cellular aspects of prostate carcinogenesis and progression. Identification of cancer initiating cells and therapies against these population(s) is a promising way forward to fight this disease.

We invite investigators to contribute original research articles as well as review articles that bridge the laboratory and the clinic. We are particularly interested in articles describing molecular and cellular pathology of prostate cancer, preclinical animal models, molecular alterations or biomarkers that predict response or resistance to treatment, new insights into cancer stem cells, and current concepts in the prevention, treatment, and imaging of prostate cancer. Potential topics include, but are not limited to:

  • Preclinical animal models
  • Cancer stem cell biology
  • Diagnostic, prognostic, and predictive biomarkers
  • Noncoding RNA
  • Exosomes
  • Metastasis
  • Imaging
  • Treatment/drug development

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/urology/pcr/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 454256
  • - Research Article

Identification and Validation of Potential New Biomarkers for Prostate Cancer Diagnosis and Prognosis Using 2D-DIGE and MS

Cordelia Geisler | Nadine T. Gaisa | ... | Corinna Henkel
  • Special Issue
  • - Volume 2015
  • - Article ID 309851
  • - Editorial

Biomarker and Translational Prostate Cancer Research

Andreas Doll | Jeremy Clark | Colleen Nelson
  • Special Issue
  • - Volume 2015
  • - Article ID 762178
  • - Clinical Study

Simultaneous Treatment with Statins and Aspirin Reduces the Risk of Prostate Cancer Detection and Tumorigenic Properties in Prostate Cancer Cell Lines

M. Olivan | M. Rigau | ... | J. Morote
  • Special Issue
  • - Volume 2014
  • - Article ID 981434
  • - Review Article

From Bench to Bedside: Immunotherapy for Prostate Cancer

Brian Wan-Chi Tse | Lidija Jovanovic | ... | Pamela Joan Russell
  • Special Issue
  • - Volume 2014
  • - Article ID 376326
  • - Review Article

Role of miRNA Let-7 and Its Major Targets in Prostate Cancer

Siegfried Wagner | Anaclet Ngezahayo | ... | Ingo Nolte
  • Special Issue
  • - Volume 2014
  • - Article ID 591703
  • - Review Article

Noncoding RNAs as Novel Biomarkers in Prostate Cancer

C. G. H. Rönnau | G. W. Verhaegh | ... | J. A. Schalken
  • Special Issue
  • - Volume 2014
  • - Article ID 765207
  • - Review Article

Novel RNA Markers in Prostate Cancer: Functional Considerations and Clinical Translation

Julia M. A. Pickl | Doreen Heckmann | ... | Holger Sültmann
  • Special Issue
  • - Volume 2014
  • - Article ID 341324
  • - Review Article

Prognostic Histopathological and Molecular Markers on Prostate Cancer Needle-Biopsies: A Review

A. Marije Hoogland | Charlotte F. Kweldam | Geert J. L. H. van Leenders
  • Special Issue
  • - Volume 2014
  • - Article ID 549136
  • - Review Article

Stem Cell Based Gene Therapy in Prostate Cancer

Jae Heon Kim | Hong Jun Lee | Yun Seob Song
  • Special Issue
  • - Volume 2014
  • - Article ID 526341
  • - Review Article

Kallikreins as Biomarkers for Prostate Cancer

Sung Kyu Hong
BioMed Research International
 Journal metrics
Acceptance rate30%
Submission to final decision82 days
Acceptance to publication43 days
CiteScore2.410
Impact Factor2.197
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