BioMed Research International

Ischemia-Reperfusion Injury and Anesthesia


Publishing date
21 Mar 2014
Status
Published
Submission deadline
01 Nov 2013

Lead Editor

1Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine, Karadeniz Technical University, 61080 Trabzon, Turkey

2Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine, Karadeniz Technical University, 61000 Trabzon, Turkey

3Department of Intensive Care Medicine, Erasmus Medical Center, Erasmus University Rotterdam, 3000 CA Rotterdam, The Netherlands

4Fresenius Kabi AG, Else-Kröner-Straße 1, 61352 Bad Homburg, Germany


Ischemia-Reperfusion Injury and Anesthesia

Description

After the ischemic period reentry of the blood to tissue causes massive amounts of oxygen free radicals release. Oxygen free radicals trigger some enzymatic reactions; peroxidation of polyunsaturated fatty acids or plasma lipoproteins leads to oxidative destructions of cell membranes and the productions of toxic reactive metabolites and cell injury involving DNA, proteins, and lipids. All of these events are named ischemia-reperfusion injury (IRI). IRI is occurred on different models. On pump cardiac surgery, tourniquet application for extremity surgery, thromboembolic events and revascularization, severe hypotension, and currently very actual, organ transplantation may cause IRI. Various markers are used to detect IRI. Malonyldialdehyde (MDA), ischaemia modified albumin (IMA), catalase, peroxidase, total oxidant capacity, and total antioxidant capacity are often used for this purpose.

IRI may cause cardiopulmonary complication such as tachyarrhythmia and hypoxia. Thus a lot of studies are conducted to prevent IRI. Some of these are related anesthesia method such as regional anesthesia, inhaler general anesthesia, or total intravenous anesthesia. Some of these are related drugs such as vitamin E, propofol, n-acetyl cysteine, and dexmedetomidine.

We invite authors to submit original research and review articles that seek to define the interaction between ischemia-reperfusion injury and anesthesia. We are interested in articles that explore aspects of the effect of anesthesia on ischemia-reperfusion injury in humans and also in animal models. Potential topics include, but are not limited to:

  • The model of IRI
  • The preventive method of IRI
  • The drugs that decrease the IRI
  • The markers of IRI
  • Duration of ischemia and reperfusion
  • Inhalation anesthetic agents and IRI
  • Intravenous anesthetic drugs and IRI
  • Regional anesthesia and IRI

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/anesthesiology/isch/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 980318
  • - Editorial

Ischemia-Reperfusion Injury and Anesthesia

Alexander Zarbock | Ahmet Eroglu | ... | Martin Westphal
  • Special Issue
  • - Volume 2014
  • - Article ID 802539
  • - Research Article

Evidence for the Use of Isoflurane as a Replacement for Chloral Hydrate Anesthesia in Experimental Stroke: An Ethical Issue

Pétrault Maud | Ouk Thavarak | ... | Bordet Régis
  • Special Issue
  • - Volume 2014
  • - Article ID 846570
  • - Clinical Study

The Effects of Spinal, Inhalation, and Total Intravenous Anesthetic Techniques on Ischemia-Reperfusion Injury in Arthroscopic Knee Surgery

Müge Koşucu | İlker Coşkun | ... | Murat Topbas
  • Special Issue
  • - Volume 2014
  • - Article ID 857109
  • - Research Article

Role of Ethyl Pyruvate in Systemic Inflammatory Response and Lung Injury in an Experimental Model of Ruptured Abdominal Aortic Aneurysm

Zerrin Pulathan | Gökalp Altun | ... | Ali Civelek
  • Special Issue
  • - Volume 2014
  • - Article ID 907915
  • - Research Article

Adalimumab Ameliorates Abdominal Aorta Cross Clamping Which Induced Liver Injury in Rats

Erkan Cure | Medine Cumhur Cure | ... | Ahmet Fikret Yücel
  • Special Issue
  • - Volume 2014
  • - Article ID 821513
  • - Review Article

The Effect of Intravenous Anesthetics on Ischemia-Reperfusion Injury

Ahmet Eroglu
  • Special Issue
  • - Volume 2014
  • - Article ID 892704
  • - Research Article

The Effects of Remote Ischemic Preconditioning and N-Acetylcysteine with Remote Ischemic Preconditioning in Rat Hepatic Ischemia Reperfusion Injury Model

Ali Ihsan Uysal | Elvan Ocmen | ... | Belgin Unal Togrul
  • Special Issue
  • - Volume 2014
  • - Article ID 760323
  • - Research Article

The Effect of Dexmedetomidine on Oxidative Stress during Pneumoperitoneum

Bahanur Cekic | Sukran Geze | ... | Ahmet Mentese
  • Special Issue
  • - Volume 2014
  • - Article ID 360936
  • - Clinical Study

The Comparison of the Effects of Sevoflurane Inhalation Anesthesia and Intravenous Propofol Anesthesia on Oxidative Stress in One Lung Ventilation

Engin Erturk | Selma Topaloglu | ... | Ahmet Mentese
  • Special Issue
  • - Volume 2014
  • - Article ID 526301
  • - Review Article

Ischemia-Reperfusion Injury and Volatile Anesthetics

Engin Erturk
BioMed Research International
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