Cancer Chemoprevention
1Department of Biology, Faculty of Science, United Arab Emirates University, P.O. Box 17551, Al-Ain, UAE
2Department for Genetic Toxicology and Cancer Biology, National Institute of Biology, Večna pot 111, Ljubljana, Slovenia
3Department of Hematopathology and Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
4Institute of Pathology, University of Erlangen-Nürnberg, Erlangen, Erlangen, Germany
Cancer Chemoprevention
Description
Cancer is a leading cause of death worldwide. Conventional cancer therapies cause serious side effects and, at best, merely extend the patient's lifespan by a few years in most cancer types. Cancer control may therefore benefit from the potential that resides in alternative therapies. The demand to utilize alternative concepts or approaches to the treatment and prevention of cancer is therefore escalating. There is compelling evidence from epidemiological and experimental studies that highlight the importance of compounds derived from plants “phytochemicals” to reduce the risk of colon cancer and inhibit the development and spread of tumors in experimental animals. More than 25% of drugs used during the last 20 years are directly derived from plants, while the other 25% are chemically altered natural products. The advantages of using such compounds for cancer prevention and treatment are their relatively nontoxic nature and availability in an ingestive form.
We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts that lead to a better understanding of the molecular mechanism underlying natural-product-based chemoprevention against any type of cancer. We are equally interested in articles investigating cancer-related research areas such as drug discovery, drug targeting and delivery, novel biomarkers, and new diagnostic and/or prognostic modalities including novel high-throughput molecular tests and pharmacogenetics, stem cells, and viral and nonviral gene therapy strategies. Potential topics include, but are not limited to:
- Molecular mechanisms of cancer chemoprevention
- Novel cancer biomarkers as targets for chemoprevention
- Recent developments in drug discovery, targeting, and delivery
- Novel molecular diagnostic methods
- Pharmacogenetics
- Clinical and preclinical (animal models) studies of cancer-related chemoprevention
- Cell death pathways in cancer chemoprevention
- Dietary factors in cancer prevention
Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jbb/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: