BioMed Research International

Enhanced Cardiovascular Risk in Rheumatoid Arthritis: Elucidation, Assessment, and Management


Status
Published

1Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

2Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

3Department of Rheumatology, Hospital Universitario Marques de Valdecilla, IFIMAV, Avenida de Valdecilla S/N, 39008 Santander, Spain

4Department of Rheumatology, Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands


Enhanced Cardiovascular Risk in Rheumatoid Arthritis: Elucidation, Assessment, and Management

Description

Patients with rheumatoid arthritis (RA) experience a substantially increased risk for cardiovascular disease and mortality. High-grade systemic inflammation in RA can modify conventional cardiovascular risk factor profiles as well as directly enhance atherogenesis. However, the molecular mechanisms underlying the systemic inflammation-cardiovascular risk relation in RA have not been fully identified. Also, the contribution of disease characteristics including inflammation and their interactions with conventional cardiovascular risk factors to enhanced cardiovascular risk in RA awaits clear delineation. Finally, most of our knowledge on cardiovascular risk in RA originates in studies that were performed in developed and predominantly white populations whereas the majority of cardiovascular events presently occur in developing populations.

Congruent with these unresolved issues, recently reported evidence indicates that the application of current recommendations on cardiovascular risk stratification in RA may result in a large proportion of patients at high risk of cardiovascular disease remaining unidentified and consequently receiving inadequate preventive intervention. We are therefore interested in original manuscripts including review papers that explore cardiovascular risk in RA. Potential topics include, but are not limited to:

  • Novel cardiovascular risk factors including biomarkers in RA
  • Genetic polymorphisms associated with cardiovascular risk in RA
  • Impact of ethnicity on cardiovascular risk in RA
  • Alterations in cardiovascular risk factor profiles in RA
  • Interactions between RA characteristics and conventional risk factors and their role in enhanced cardiovascular risk
  • The use of surrogate markers of cardiovascular risk including subclinical atherosclerosis in RA
  • Impact of antirheumatic agents on cardiovascular risk in RA
  • Impact of cardiovascular drugs on cardiovascular risk in RA
  • Cardiovascular preventive measures and outcome in patients with RA

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/cdi/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/rheumatology/ecr/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 850671
  • - Editorial

Enhanced Cardiovascular Risk in Rheumatoid Arthritis: Elucidation, Assessment, and Management

Patrick H. Dessein | Anne G. Semb | ... | Calin D. Popa
  • Special Issue
  • - Volume 2015
  • - Article ID 619023
  • - Research Article

Assessment of the Body Composition and Parameters of the Cardiovascular Risk in Juvenile Idiopathic Arthritis

Ewa Jednacz | Lidia Rutkowska-Sak
  • Special Issue
  • - Volume 2015
  • - Article ID 342649
  • - Research Article

Serum Levels of Anticyclic Citrullinated Peptide Antibodies, Interleukin-6, Tumor Necrosis Factor-α, and C-Reactive Protein Are Associated with Increased Carotid Intima-Media Thickness: A Cross-Sectional Analysis of a Cohort of Rheumatoid Arthritis Patients without Cardiovascular Risk Factors

Mónica Vázquez-Del Mercado | Lourdes Nuñez-Atahualpa | ... | Javier Andrade-Garduño
  • Special Issue
  • - Volume 2015
  • - Article ID 809514
  • - Research Article

Increased Incidence of Atrial Fibrillation in Patients with Rheumatoid Arthritis

A. Kirstin Bacani | Cynthia S. Crowson | ... | Eric L. Matteson
  • Special Issue
  • - Volume 2015
  • - Article ID 515280
  • - Research Article

EULAR Task Force Recommendations on Annual Cardiovascular Risk Assessment for Patients with Rheumatoid Arthritis: An Audit of the Success of Implementation in a Rheumatology Outpatient Clinic

Eirik Ikdahl | Silvia Rollefstad | ... | Anne Grete Semb
  • Special Issue
  • - Volume 2015
  • - Article ID 318364
  • - Research Article

Lack of Association between JAK3 Gene Polymorphisms and Cardiovascular Disease in Spanish Patients with Rheumatoid Arthritis

Mercedes García-Bermúdez | Raquel López-Mejías | ... | Miguel A. González-Gay
  • Special Issue
  • - Volume 2014
  • - Article ID 510305
  • - Clinical Study

Modifications in Lipid Levels Are Independent of Serum TNF-α in Rheumatoid Arthritis: Results of an Observational 24-Week Cohort Study Comparing Patients Receiving Etanercept Plus Methotrexate or Methotrexate as Monotherapy

Norma Alejandra Rodriguez-Jimenez | Carlos E. Garcia-Gonzalez | ... | Laura Gonzalez-Lopez
  • Special Issue
  • - Volume 2014
  • - Article ID 826095
  • - Review Article

Cardiovascular Disease Risk amongst African Black Patients with Rheumatoid Arthritis: The Need for Population Specific Stratification

Ahmed Solomon | Linda Tsang | ... | Patrick H. Dessein
BioMed Research International
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Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
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