BioMed Research International

New Insights into Malignant B-Cell Disorders


Publishing date
05 Sep 2014
Status
Published
Submission deadline
18 Apr 2014

1Hematology Section, First Department of Propaedeutic Internal Medicine, Laikon Hospital, Athens Medical School, Athens, Greece

2Department of Clinical Research, Higashi Nagoya National Hospital, Nagoya, Japan

3Hematology Clinic, Athens Medical Center, Athens, Greece


New Insights into Malignant B-Cell Disorders

Description

Mature B-cell disorders comprise a very wide range of entities and disease groups, including aggressive B-cell lymphomas, Hodgkin lymphoma, plasma cell dyscrasias, indolent lymphomas, and chronic lymphocytic leukemia.

These diseases present themselves with cellular and clinical pictures, and patients’ outcomes as well as adequate treatment modalities may differ considerably. However, in spite of enormous differences, their common origin dictates resembling features, leading to difficulty in differential diagnosis in some occasions.

An increasing knowledge of disease biology, innovative diagnostic techniques, and novel drugs has resulted in improvement of diagnosis, prognosis, and treatment although some confusion may still occur.

We invite investigators to submit original research articles as well as review articles aiming to contribute to rationally understand and apply scientific improvements in B-cell disorders.

We are particularly interested in articles explaining underlying disease biology, describing improvement of diagnostic tools including sensitive biochemical, immunohistochemical, immunophenotypic, molecular, genetic, and imaging techniques, presenting new entities requiring specific approaches and reporting on therapeutic results with novel drugs and monoclonal antibodies. Potential topics include, but are not limited to:

  • Prognostic factors and genetic biomarkers
  • Aggressive B-cell lymphomas originating from different pathways; clinical implications
  • Mechanisms of malignant B-cell (or plasma cell) regulation and/or escape from apoptosis
  • Definitions and implications of complete remission in multiple myeloma
  • Evaluation of minimal residual disease in B-cell disorders
  • Optimal use of PET-scan in lymphomas monitoring and prognosis
  • Diagnostic and therapeutic challenges for composite lymphomas
  • Differential diagnosis of B-cell disorders with plasmacytic differentiation
  • New biology-driven treatments

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/hematology/indis/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 128084
  • - Editorial

New Insights into Malignant B-Cell Disorders

Marie-Christine Kyrtsonis | Kazuyuki Shimizu | ... | Gerassimos A. Pangalis
  • Special Issue
  • - Volume 2015
  • - Article ID 104912
  • - Review Article

Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future

Marisa Granato | Roberta Santarelli | ... | Mara Cirone
  • Special Issue
  • - Volume 2014
  • - Article ID 265840
  • - Research Article

Lenalidomide Induces Immunomodulation in Chronic Lymphocytic Leukemia and Enhances Antitumor Immune Responses Mediated by NK and CD4 T Cells

Andrea Acebes-Huerta | Leticia Huergo-Zapico | ... | Segundo Gonzalez
  • Special Issue
  • - Volume 2014
  • - Article ID 258917
  • - Review Article

New Insights into Monoclonal B-Cell Lymphocytosis

Christina Kalpadakis | Gerassimos A. Pangalis | ... | Maria K. Angelopoulou
  • Special Issue
  • - Volume 2014
  • - Article ID 809103
  • - Research Article

Clonotypic Analysis of Immunoglobulin Heavy Chain Sequences in Patients with Waldenström’s Macroglobulinemia: Correlation with MYD88 L265P Somatic Mutation Status, Clinical Features, and Outcome

Loizos Petrikkos | Marie-Christine Kyrtsonis | ... | Panayiotis Panayiotidis
  • Special Issue
  • - Volume 2014
  • - Article ID 835138
  • - Review Article

New Insights in the Mobilization of Hematopoietic Stem Cells in Lymphoma and Multiple Myeloma Patients

Maria K. Angelopoulou | Pantelis Tsirkinidis | ... | Panayiotis Tsirigotis
  • Special Issue
  • - Volume 2014
  • - Article ID 159632
  • - Research Article

Serum Soluble TACI, a BLyS Receptor, Is a Powerful Prognostic Marker of Outcome in Chronic Lymphocytic Leukemia

Marie-Christine Kyrtsonis | Katerina Sarris | ... | Panayiotis Panayiotidis
  • Special Issue
  • - Volume 2014
  • - Article ID 106713
  • - Research Article

PARP1-Driven Apoptosis in Chronic Lymphocytic Leukemia

Panagiotis T. Diamantopoulos | Maria Sofotasiou | ... | Nora-Athina Viniou
  • Special Issue
  • - Volume 2014
  • - Article ID 965384
  • - Review Article

Targeted Therapy for HM1.24 (CD317) on Multiple Myeloma Cells

Takeshi Harada | Shuji Ozaki
BioMed Research International
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Acceptance rate31%
Submission to final decision81 days
Acceptance to publication56 days
CiteScore2.410
Impact Factor2.197
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