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Erratum | Open Access
Nataša Nikolić, Magdalena Rhedin, Arild C. Rustan, Len Storlien, G. Hege Thoresen, Maria Strömstedt, "Erratum to “Overexpression of PGC-1
Erratum to “Overexpression of PGC-1 Increases Fatty Acid Oxidative Capacity of Human Skeletal Muscle Cells”
Nataša Nikolić,1 Magdalena Rhedin,2 Arild C. Rustan
,1 Len Storlien,3 G. Hege Thoresen,1 and Maria Strömstedt21Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, P.O. Box 1068 Blindern, N-0316 Oslo, Norway
2AstraZeneca Reseach and Development, SE-43185 Mölndal, Sweden
3Boden Institute of Obesity, Nutrition and Exercise, University of Sydney, Sydney, NSW 2006, Australia
Unfortunately there was a mistake in Figure 7. The primer used for mRNA expression was actually MYH1, which regulates expression of MHC type IIx muscle fibers and not MHC type I as stated in the figure. However, we have repeated the experiment with the correct primer MYH7 (acc_no. NM000257.2, F: CTCTGCACAGGGAAAATCTGAA, R: CCCCTGGAGACTTTGTCTCATT), and the new Figure 7 is shown here. This makes no difference to the conclusions of the paper. There was no significant change in mRNA of MHCI (MYH7), neither was the MHCI/MHCIIa mRNA ratio significantly increased. However, the last sentence in Section 3 (page 7) should be slightly changed: “Thus, the MHCI/MHCIIa mRNA ratio was approximately doubled in cells overexpressing PGC-1 compared to control cells infected with empty vector (from 4.5 to 9.2, resp.).”
Copyright
Copyright © 2013 Nataša Nikolić et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
