Impact of Highly Saturated versus Unsaturated Fat Intake on Carbohydrate Metabolism and Vascular Reactivity in Rat

Figure 4

Effect of L-NAME on the contractile response to Phe. (a) Concentration-response curves to phenylephrine (0.01–100 µM) in aortic rings from control, olive oil, palm olein, and lard diets in absence and in presence of L-NAME (10 µmol/L). (b) Histogram represents the difference in area under curve between contractions with and without L-NAME for each group expressed as percentage of Phe effect. Results were expressed as mean values ± SD, n = 7-8 animals per group. The limit of statistical significance was set at . Histogram bars with different letters (a, b, c) are significantly different. AUC: area under the curve; L-NAME: nitro-L-arginine methyl ester.

(a)

(b)