Impact of Highly Saturated versus Unsaturated Fat Intake on Carbohydrate Metabolism and Vascular Reactivity in Rat

Table 2

Body weight and metabolic parameters in various groups.

	Control	Olive oil	Palm olein	Lard
Body weight (g)	519 ± 25^a	588 ± 49^b	605 ± 52^b	611 ± 66^b	0.0083
Total cholesterol (mmol/L)	2.00 ± 0.41^a	1.72 ± 0.28^ab	1.89 ± 0.46^a	1.55 ± 0.26^b	0.0301
HDL cholesterol (mmol/L)	1.49 ± 0.30^a	1.33 ± 0.20^ab	1.48 ± 0.36^a	1.06 ± 0.33^b	0.0106
Triglycerides (mmol/L)	1.18 ± 0.55	1.01 ± 0.31	1.21 ± 0.60	1.01 ± 0.42	NS
Glucose (mmol/L)	7.73 ± 0.24^a	8.35 ± 0.35^ab	8.73 ± 0.21^b	7.31 ± 0.32^c	0.009
Insulin (µg/L)	2.13 ± 0.98	3.37 ± 1.01	5.17 ± 1.24	3.73 ± 0.94	NS
HOMA-IR	17.3 ± 2.5^a	31.6 ± 10.3^a	55.1 ± 10.8^b	30.3 ± 8.3^a	0.023
SOD (U/mL)	324.2 ± 5.4^a	326.7 ± 6.6^a	262.1 ± 8.8^b	275.9 ± 6.2^b	0.0021

Results were expressed as mean values ± SD, n = 7-8 animals per group. The limit of statistical significance was set at . The group mean values with different letters (a, b, c) are significantly different. HDL: high density lipoprotein; HOMA-IR: Homeostasis model assessment of insulin resistance; SOD: superoxide dismutase; NS: not significant.