Impact of Highly Saturated versus Unsaturated Fat Intake on Carbohydrate Metabolism and Vascular Reactivity in Rat

Table 3

Effects of diets on half maximum effective concentration (EC₅₀) for agonists (Phe, KCl) and antagonists (Ach, SNP).

	Control	Olive oil	Palm olein	Lard
EC50 KCl (mM)	7.97 ± 0.5^a	9.03 ± 0.7^ab	7.63 ± 0.8^a	10.58 ± 0.6^b	0.03
EC50 phe (mM)	368 ± 41	254 ± 27	279 ± 30	240 ± 22	NS
EC50 ach (nM)	206 ± 50	157 ± 46	164 ± 32	166 ± 30	NS
EC50 SNP (nM)	6.5 ± 0.5	9.5 ± 0.8	6.9 ± 0.5	9.9 ± 1.2	NS

Results were expressed as mean values ± SD, n = 7–8 animals per group. The limit of statistical significance was set at . The group mean values with different letters (a, b, c) are significantly different. Ach: acetylcholine; KCl: potassium chloride, Phe: phenylephrine; SNP: sodium nitroprusside.