Table of Contents Author Guidelines Submit a Manuscript
Critical Care Research and Practice
Volume 2012 (2012), Article ID 102483, 6 pages
http://dx.doi.org/10.1155/2012/102483
Research Article

Comparison of Different Methods for the Calculation of the Microvascular Flow Index

1Servicio de Terapia Intensiva, Clínica Bazterrica, Juncal 3002, C1425AYN Buenos Aires, Argentina
2Cátedra de Farmacología Aplicada, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, 60 y 120, 1900 La Plata, Argentina
3Servicio de Terapia Intensiva, Sanatorio Otamendi y Miroli, Azcuénaga 870, C1115AAB Buenos Aires, Argentina
4Department of Intensive Care Adults Erasmus MC, University Medical Centre Rotterdam, 3000 CA Rotterdam, The Netherlands

Received 24 December 2011; Revised 16 February 2012; Accepted 2 March 2012

Academic Editor: Michael Piagnerelli

Copyright © 2012 Mario O. Pozo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. V. S. Kanoore Edul, C. Enrico, B. Laviolle, A. Risso Vazquez, C. Ince, and A. Dubin, “Quantitative assessment of the microcirculation in healthy volunteers and in septic shock patients,” Critical Care Medicine, vol. 40, no. 5, pp. 1443–1448, 2012. View at Google Scholar
  2. W. Groner, J. W. Winkelman, A. G. Harris et al., “Orthogonal polarization spectral imaging: a new method for study of the microcirculation,” Nature Medicine, vol. 5, no. 10, pp. 1209–1213, 1999. View at Publisher · View at Google Scholar · View at Scopus
  3. P. T. Goedhart, M. Khalilzada, R. Bezemer, J. Merza, and C. Ince, “Sidestream Dark Field (SDF) imaging: a novel stroboscopic LED ring-based imaging modality for clinical assessment of the microcirculation,” Optics Express, vol. 15, no. 23, pp. 15101–15114, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. D. De Backer, J. Creteur, J. C. Preiser, M. J. Dubois, and J. L. Vincent, “Microvascular blood flow is altered in patients with sepsis,” American Journal of Respiratory and Critical Care Medicine, vol. 166, no. 1, pp. 98–104, 2002. View at Publisher · View at Google Scholar · View at Scopus
  5. S. Trzeciak, R.P. Dellinger, J. E. Parrillo et al., “Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival,” Annals of Emergency Medicine, vol. 49, no. 1, pp. 88–98, 2007. View at Google Scholar
  6. Y. Sakr, M. J. Dubois, D. De Backer, J. Creteur, and J. L. Vincent, “Persistent-microcirculatory alterations are associated with organ failure and death in patients with septic shock,” Critical Care Medicine, vol. 32, no. 9, pp. 1825–1831, 2004. View at Publisher · View at Google Scholar · View at Scopus
  7. A. Morelli, A. Donati, C. Ertmer et al., “Levosimendan for resuscitating the microcirculation in patients with septic shock: a randomized controlled study,” Critical Care, vol. 14, no. 6, article R232, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. A. Dubin, M. O. Pozo, C. A. Casabella et al., “Increasing arterial blood pressure with norepinephrine does not improve microcirculatory blood flow: a prospective study,” Critical Care, vol. 13, no. 3, article R92, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Dubin, M. O. Pozo, C. A. Casabella et al., “Comparison of 6% hydroxyethyl starch 130/0.4 and saline solution for resuscitation of the microcirculation during the early goal-directed therapy of septic patients,” Journal of Critical Care, vol. 25, no. 4, pp. 659.e1–659.e8, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. D. De Backer, S. Hollenberg, C. Boerma et al., “How to evaluate the microcirculation: report of a round table conference,” Critical Care, vol. 11, article R101, 2007. View at Publisher · View at Google Scholar · View at Scopus
  11. E. C. Boerma, K. R. Mathura, P. H. van der Voort, P. E. Spronk, and C. Ince, “Quantifying bedside-derived imaging of microcirculatory abnormalities in septic patients: a prospective validation study,” Critical Care, vol. 9, no. 6, pp. R601–R606, 2005. View at Google Scholar · View at Scopus
  12. R. C. Arnold, J. E. Parrillo, R. Phillip Dellinger et al., “Point-of-care assessment of microvascular blood flow in critically ill patients,” Intensive Care Medicine, vol. 35, no. 10, pp. 1761–1766, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. A. Dubin, M. O. Pozo, G. Ferrara et al., “Systemic and microcirculatory responses to progressive hemorrhage,” Intensive Care Medicine, vol. 35, no. 3, pp. 556–564, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. V. S. Edul, G. Ferrara, M. O. Pozo et al., “Failure of nitroglycerin (glyceryl trinitrate) to improve villi hypoperfusion in endotoxaemic shock in sheep,” Critical Care and Resuscitation, vol. 13, no. 4, pp. 252–261, 2011. View at Google Scholar
  15. J. G. G. Dobbe, G. J. Streekstra, B. Atasever, R. van Zijderveld, and C. Ince, “Measurement of functional microcirculatory geometry and velocity distributions using automated image analysis,” Medical and Biological Engineering and Computing, vol. 46, no. 7, pp. 659–670, 2008. View at Publisher · View at Google Scholar · View at Scopus
  16. J. M. Bland and D. G. Altman, “Statistical methods for assessing agreement between two methods of clinical measurement,” The Lancet, vol. 1, no. 8476, pp. 307–310, 1986. View at Google Scholar · View at Scopus