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Critical Care Research and Practice
Volume 2012 (2012), Article ID 861867, 6 pages
Clinical Study

Value of Chest Radiographic Pattern in RSV Disease of the Newborn: A Multicenter Retrospective Cohort Study

1Division of Neonatology, São João Hospital, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal
2Division of Pediatric and Neonatal Intensive Care, Santo António General Hospital, 4099-001 Porto, Portugal
3Unit of Neonatology, Júlio Dinis Maternity, 4050-371 Porto, Portugal
4Unit of Neonatology, MªPia Children's Hospital, 4050-311 Porto, Portugal
5Unit of Neonatology, Vila Nova de Gaia Hospital, 4434-502 Vila Nova de Gaia, Portugal
6Unit of Neonatology, Pedro Hispano Hospital, 4454-509 Matosinhos, Portugal
7Unit of Neonatology, Senhora da Oliveira Hospital, 4835-044 Guimarães, Portugal
8Division of Neonatology, Braga Hospital, 4710-243 Braga, Portugal

Received 31 August 2012; Revised 10 November 2012; Accepted 11 November 2012

Academic Editor: Anton van Kaam

Copyright © 2012 Américo Gonçalves et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Respiratory syncytial virus (RSV) lower respiratory tract infection is the most common viral respiratory infection in infants. Several authors have sought to determine which risk factors are the best predictors for severe RSV disease. Our aim was to evaluate if a specific chest radiographic pattern in RSV disease can predict the disease severity. We conducted a multicenter retrospective cohort study in term and preterm neonates with confirmed lower respiratory tract RSV infection, admitted to neonatal intensive care units (NICU) from 2000 to 2010. To determine which factors independently predicted the outcomes, multivariate logistic regression analysis was performed. A total of 259 term and preterm neonates were enrolled. Patients with a consolidation pattern on the chest radiograph at admission ( ) had greater need for invasive mechanical ventilation (OR: 2.5; ), respiratory support (OR: 2.3; ), supplemental oxygen (OR: 3.0; ), and prolonged stay in the NICU (>7 days) (OR: 1.8; ). Newborns with a consolidation pattern on admission chest radiograph had a more severe disease course, with greater risk of invasive mechanical ventilation, respiratory support, supplemental oxygen, and prolonged hospitalization.